27 December 2020 : Database Analysis
Expression of the Topoisomerase II Alpha (TOP2A) Gene in Lung Adenocarcinoma Cells and the Association with Patient Outcomes
Xiaomei Du1AEFG, Zhiwen Xue1BF, Jianning Lv1BC, Heidou Wang2ACG*DOI: 10.12659/MSM.929120
Med Sci Monit 2020; 26:e929120
Table 1 Correlation analysis between TOP2A mRNA and pathological features of LUAD.
| Comparison | Statistical significance |
|---|---|
| Normal--Caucasian | 1.62E-12 |
| Normal--African-American | 1.94E-10 |
| Normal--Asian | 3.19E-02 |
| Normal--Stage 1 | <1E-12 |
| Normal--Stage 2 | 1.62E-12 |
| Normal--Stage 3 | 1.62E-12 |
| Normal--Stage 4 | 1.54E-05 |
| Normal--Male | 1.62E-12 |
| Normal--Female | 1.62E-12 |
| Male--Female | 4.30E-02 |
| Normal--Age (41–60 yrs) | <1E-12 |
| Normal--Age (61–80 yrs) | 1.62E-12 |
| Normal--Age (81–100 yrs) | 2.13E-05 |
| Normal--Non smoker | 1.09E-12 |
| Normal--Smoker | 1.62E-12 |
| Normal--Reformed smoker 1 | 1.62E-12 |
| Normal--Reformed smoker 2 | <1E-12 |
| Non smoker--Smoker | 1.38E-04 |
| Non smoker--Reformed smoker 2 | 1.26E-02 |
| Smoker--Reformed smoker 1 | 2.45E-08 |
| Reformed smoker 1--Reformed smoker 2 | 2.39E-06 |
| Normal--N0 | <1E-12 |
| Normal--N1 | 1.62E-12 |
| Normal--N2 | 1.64E-12 |
| Normal--N3 | <1E-12 |
| N0--N1 | 5.76E-01 |
| N0--N2 | 2.35E-01 |
| N0--N3 | 1.41E-06 |
| N1--N3 | 1.48E-02 |
| N0 – no regional lymph node metastasis; N1 – metastases in 1 to 3 axillary lymph nodes; N2 – metastases in 4 to 9 axillary lymph nodes; N3 – metastases in 10 or more axillary lymph nodes. | |