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27 December 2020: Database Analysis

Expression of the Topoisomerase II Alpha (TOP2A) Gene in Lung Adenocarcinoma Cells and the Association with Patient Outcomes

Xiaomei Du 1AEFG , Zhiwen Xue 1BF , Jianning Lv 1BC , Heidou Wang 2ACG*

DOI: 10.12659/MSM.929120

Med Sci Monit 2020; 26:e929120

Table 1 Correlation analysis between TOP2A mRNA and pathological features of LUAD.

ComparisonStatistical significance
Normal--Caucasian1.62E-12
Normal--African-American1.94E-10
Normal--Asian3.19E-02
Normal--Stage 1
Normal--Stage 21.62E-12
Normal--Stage 31.62E-12
Normal--Stage 41.54E-05
Normal--Male1.62E-12
Normal--Female1.62E-12
Male--Female4.30E-02
Normal--Age (41–60 yrs)
Normal--Age (61–80 yrs)1.62E-12
Normal--Age (81–100 yrs)2.13E-05
Normal--Non smoker1.09E-12
Normal--Smoker1.62E-12
Normal--Reformed smoker 11.62E-12
Normal--Reformed smoker 2
Non smoker--Smoker1.38E-04
Non smoker--Reformed smoker 21.26E-02
Smoker--Reformed smoker 12.45E-08
Reformed smoker 1--Reformed smoker 22.39E-06
Normal--N0
Normal--N11.62E-12
Normal--N21.64E-12
Normal--N3
N0--N15.76E-01
N0--N22.35E-01
N0--N31.41E-06
N1--N31.48E-02
N0 – no regional lymph node metastasis; N1 – metastases in 1 to 3 axillary lymph nodes; N2 – metastases in 4 to 9 axillary lymph nodes; N3 – metastases in 10 or more axillary lymph nodes.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750