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20 April 2021 : Clinical Research  

Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts

Jiaxin Guan1BCEF, Lu Gan1B, Di Jin1ACD, Xiaowei Wu1B, Luyang Cheng1C, Meiling Liu1C, Ying Fan1B, Jing Zhou2B, Hanlu Zhang1B, Yina Zhang1AFG*, Ping Zhou1FG

DOI: 10.12659/MSM.929170

Med Sci Monit 2021; 27:e929170

Table 1 Clinical characteristics of the participants.

CharacteristicControl group (n=25)PMOP group (n=28)P value
Age, years57.00±5.1959.50±4.370.063
Height, cm161.80±5.02159.27±4.210.052
Weight, kg60.64±9.0856.39±6.740.057
BMI, kg/m23.11±2.9922.22±2.370.233
Lymphocyte count, 10/L2.09±0.611.70±0.620.137
Monocyte count, 10/L0.32±0.180.26±0.120.103
T-score
 Lumbar vertebra−0.31±0.61−3.10±0.66<0.001*
 Femur−0.24±0.60−2.74±0.52<0.001*
 Forearm−0.47±0.84−3.18±1.37<0.001*
BMD, g/cm
 Lumbar vertebra1.003±0.0660.709±0.064<0.001*
 Femur0.813±0.0760.556±0.066<0.001*
 Forearm0.655±0.0550.504±0.076<0.001*
Data are presented as mean±SD or median±quartile.
*

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750