Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts

Jiaxin Guan; Lu Gan; Di Jin; Xiaowei Wu; Luyang Cheng; Meiling Liu; Ying Fan; Jing Zhou; Hanlu Zhang; Yina Zhang; Ping Zhou

doi:10.12659/MSM.929170

20 April 2021 : Clinical Research

Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts

Jiaxin Guan^1BCEF, Lu Gan^1B, Di Jin^1ACD, Xiaowei Wu^1B, Luyang Cheng^1C, Meiling Liu^1C, Ying Fan^1B, Jing Zhou^2B, Hanlu Zhang^1B, Yina Zhang^1AFG*, Ping Zhou^1FG

DOI: 10.12659/MSM.929170

Med Sci Monit 2021; 27:e929170

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Table 4 Pearson analysis of correlations between hsa_circ_0021739 and clinical characteristics of PMOP patients.

Characteristic	r	P value
Age, years	0.157	0.261
Height, cm	−0.264	0.057
Weight, kg	−0.219	0.116
BMI, kg/m	−0.118	0.399
Lymphocyte count, 10/L	−0.260	0.060
Monocyte count, 10/L	−0.017	0.090
T-score
Lumbar vertebra	−0.542	<0.001
Femur	−0.459	<0.001
Forearm	−0.349	0.011

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Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts

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