Contribution of Interstitial Cells of Cajal to Gastrointestinal Stromal Tumor Risk

24 March 2021 : Clinical Research

Qi Wang^1ABEG, Zhen-peng Huang^2ACDEF*, Yu Zhu^3B, Fei Fu^1B, Lin Tian^1ABDG

DOI: 10.12659/MSM.929575

Med Sci Monit 2021; 27:e929575

Background Material and Methods Results Discussion Conclusions References

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Table 1 The clinical and pathological characteristics of GIST patients.

	Number/size	Percentage (%)/mean/median

Very low risk	44	36.07
Low risk	29	23.77
Intermediate risk	16	13.11
High risk	33	27.05
^#
General
Male	58	47.54
Female	64	52.46
Very low risk
Male	24	54.55
Female	20	45.46
Low risk
Male	19	65.52
Female	10	34.48
Intermediate risk
Male	6	37.5
Female	10	62.5
High risk
Male	9	27.27
Female	24	72.73
^*
General	31–82	58.69±9.90
Very low risk	37–77	57.11±9.69
Low risk	31–77	59.64±11.10
Intermediate risk	50–78	63.44±8.68
High risk	40–82	58.69±9.90

Esophagus	3	2.46
Stomach	87	71.31
Small intestine	7	5.74
Colon and rectum	14	11.47
Omentum and mesentery	10	8.20
Liver	1	0.82

Esophagus	0.5–2	0.7
Stomach	0.5–16	2.25
Small intestine	3–14	8
Colon and rectum	0.8–12	8
Peritoneum	7–20	14
Liver	5	–
^# χ=2.4778, =0.0132; ^* =−0.990, =0.327. Most of GIST cases were very low-risk and low-risk. Male patients were more likely to have very low-risk and low-risk GISTs, whereas women were more likely to have high-risk GISTs (χ=2.4778, P=0.0132). Age at GIST diagnosis ranged from 31 to 82 years (58.69±9.90), but was not significantly associated with GIST risk (=−0.990, P=0.327). Most GISTs were located in the stomach. The size of tumors varied between 0.5 and 20 cm.

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