06 September 2021 : Animal Research
Effects of Cyanoacrylate in Rabbits with Induced Achilles Tendon Rupture
Mehmet Murat Bala
1AE*, Abdullah Alper Şahin 2B, Mehmet Boz 3C, Yasin Durukan 4D, Tülin Fırat 5E, Murat Pakdil 6F, Kutay Engin Özturan 7G
DOI: 10.12659/MSM.929709
Med Sci Monit 2021; 27:e929709
Table 2 Comparisons of histopathological variables were conducted at week 4 and week 6.
| Histopathological variables | Week 4 (n=16) | Week 6 (n=16) | ||||
|---|---|---|---|---|---|---|
| Control (n=8) | Experiment (n=8) | p* | Control (n=8) | Experiment (n=8) | p* | |
| Granulation | 0 (0%) | 8 (100%) | <0.001** | 1 (12.5%) | 7 (87.5%) | 0.010** |
| Foreign body giant cell | 0 (0%) | 8 (100%) | <0.001** | 0 (0%) | 7 (87.5%) | 0.001** |
| Inflammation | 6 (75%) | 6 (75%) | 1.000 | 4 (50%) | 7 (87.5%) | 0.282 |
| Neovascularization degree | ||||||
| 0 | 0 (0%) | 0 (0%) | 1.000 | 0 (0%) | 0 (0%) | 1.000 |
| 1 | 0 (0%) | 1 (12.5%) | 0 (0%) | 0 (0%) | ||
| 2 | 2 (25%) | 1 (12.5%) | 1 (12.5%) | 1 (12.5%) | ||
| 3 | 6 (75%) | 6 (75%) | 7 (87.5%) | 7 (87.5%) | ||
| Fibrillary collagen alignment | ||||||
| Irregular | 3 (37.5%) | 3 (37.5%) | 1.000 | 7 (87.5%) | 6 (75.0%) | 1.000 |
| Regular | 5 (67.5%) | 5 (67.5%) | 1 (12.5%) | 2 (25.0%) | ||
| Fibroblastic activity | ||||||
| 1 | 1 (12.5%) | 0 (0%) | 1.000 | 3 (37.5%) | 0 (0%) | 0.200 |
| 2 | 7 (87.5%) | 8 (100%) | 5 (67.5%) | 8 (100%) | ||
| * Fisher’s exact test; ** statistically significant at α=0.05. | ||||||