Anti-Psoriatic Effects of Middle Fragment of Chlamydial Plasmid-Encoded Protein pGP3 in an Imiquimod-Induced Psoriasis Mouse Model

05 June 2021 : Animal Research

Yiming Zhang^1A, Miaomiao Ma^2A, Jun Li^3D, Yingye Wu^2C, Lu Xue^2C, Rongrong Zhao^2B, Lu Wang^2E, Shuping Hou^2G, Huiping Wang^2G*

DOI: 10.12659/MSM.929781

Med Sci Monit 2021; 27:e929781

Background Material and Methods Results Discussion Conclusions References

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Table 1 Experimental grouping.

	Normal	IMQ	IM-pGP3	IM-pGP3M	IM-PBS
IMQ	\	√	√	√	√
pGP3	\	\	pGP3	\	\
pGP3M	\	\	\	pGP3M	\
IMQ – imiquimod; PBS – phosphate-buffered saline; IM – intramuscular. The mice were divided into 5 groups (8 mice/group): Normal group, not administered with drug or IMQ; IMQ group, administered with IMQ; IM-pGP3, administered with IMQ and intramuscularly injected with pGP3; IM-pGP3M, administered with IMQ and intramuscularly injected with pGP3M, IM-PBS, administered with IMQ and intramuscularly injected with phosphate-buffered saline (PBS).

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