Anti-Psoriatic Effects of Middle Fragment of Chlamydial Plasmid-Encoded Protein pGP3 in an Imiquimod-Induced Psoriasis Mouse Model

05 June 2021 : Animal Research

Yiming Zhang^1A, Miaomiao Ma^2A, Jun Li^3D, Yingye Wu^2C, Lu Xue^2C, Rongrong Zhao^2B, Lu Wang^2E, Shuping Hou^2G, Huiping Wang^2G*

DOI: 10.12659/MSM.929781

Med Sci Monit 2021; 27:e929781

Background Material and Methods Results Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Table 3 Comparison of epidermis thickness on day 8.

Group	Case	Epidermis thickness (μm)
Control	8	10.03±1.51
IMQ	8	94.26±19.45
IM-PBS	8	89.83±16.56
IM-pGP3	8	70.15±12.89^*
IM-pGP3M	8	69.59±13.94^*
IMQ – imiquimod; PBS – phosphate-buffered saline; IM – intramuscular. Epidermis was significantly thinner in mice treated with pGP3 and pGP3M than in mice treated with the IM-PBS group on day 8. Results are shown as mean±SD. ^*

Back to the Article