15 March 2021>: Lab/In Vitro Research
Long Noncoding RNA TCONS_00068220 Promotes Breast Cancer Progression by Regulating Epithelial-Mesenchymal Transition Marker E-Cadherin
Xiao Liu 12ABEF , Xingsong Tian 1ACDGDOI: 10.12659/MSM.929832
Med Sci Monit 2021; 27:e929832
Table 1 The correlation between TCONS_00068220 expression level and clinicopathological features of breast cancer patients.
Characteristics | TCONS_00068220 level | P-value | ||
---|---|---|---|---|
High (n, %) | Low (n, %) | |||
Age (years) | ≥50 | 19 (63.3) | 24 (80.0) | 0.153 |
11 (36.7) | 6 (20.0) | |||
Her-2 | Negative | 21 (70.0) | 19 (63.3) | 0.239 |
Positive | 9 (30.0) | 11 (36.7) | ||
TNBC | TNBC | 18 (60.0) | 17 (56.7) | 0.135 |
Non-TNBC | 12 (40.0) | 13 (43.3) | ||
Ki67 | High index | 25 (83.3) | 16 (53.3) | 0.042 |
Low index | 5 (16.7) | 14 (46.7) | ||
Lymphatic metastasis | Negative | 6 (20.0) | 19 (63.3) | 0.000 |
Positive | 24 (80.0) | 11 (36.7) | ||
Differentiation status | Well/moderate | 7 (23.3) | 18 (60.0) | 0.012 |
Poor | 23 (76.7) | 12 (40.0) | ||
TNM stage | I–II | 20 (66.7) | 13 (43.3) | 0.014 |
III–IV | 10 (33.3) | 17 (56.7) | ||
TNBC – triple-negative breast cancer; TNM – tumor, node, metastasis. |