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17 September 2021 : Clinical Research  

Factors Associated with Recurrence of Hepatocellular Carcinoma in 197 Patients Following Transarterial Chemoembolization: A Retrospective Study from a Single Center

Hongsheng Zhang1ABCE*, Xiaodong Zhao2AEF, Wenhai Yu1BC

DOI: 10.12659/MSM.929879

Med Sci Monit 2021; 27:e929879

Table 2 Influencing factors for ER after TACE in HCC patients.

Characteristics, n (%)βS.Eχ2PHR95% CI
LowerUpper
Sex
 Male0.4330.2692.5900.1081.5430.9102.615
 FemaleRef
Age−0.0130.0111.4780.2240.9870.9661.008
BMI, kg/m
Ref
 ≥23.9−0.5010.1777.9890.0050.6060.4280.857
Maximum tumor diameter, cm, M(Q1,Q3)0.3230.029120.2841.3811.3031.463
Adjacent lobe invasion
 NoRef
 Yes1.4790.18365.1704.3903.0656.287
Extrathoracic metastasis
 NoRef
 Yes1.2940.4239.3590.0023.6481.5928.357
Vascular invasion
 NoRef
 Yes2.0690.25168.1017.9134.84212.934
Lymph node metastasis
 NoRef
 Yes1.4210.28425.0004.1412.3737.229
Child-Pugh score
 ARef
 B0.815920.1928217.90532.2611.5503.300
 C0.381130.715730.28360.59441.4640.3605.953
BCLC staging
 Very early/early stageRef
 Intermediate stage1.434660.2622229.93344.1982.5117.019
 Advanced/end stage3.260310.32136102.930426.05813.88048.918
WBC, 10/L0.1040.0387.4960.0061.1091.0301.194
RBC, 10/L−0.3610.1485.9710.0150.6970.5220.931
HGB, g/L−0.0150.00412.5720.9860.9780.994
PLT, 10/L0.0040.00112.2681.0041.0021.007
NEUT, 10/L0.1580.04313.7001.1711.0771.273
LY, 10/L−0.3670.1456.3850.0120.6930.5210.921
AST/ALT, μ/L0.3340.07918.0051.3971.1970.334
TBIL, μmol/L0.0070.0035.8370.0161.0071.0011.013
ALB, g/L−0.0670.01423.9490.9350.9110.961
GGT, U/L0.00240.7811.0021.0021.003
D-dimer, ng/mL0.2170.05813.9251.2431.1091.393
NLR0.1730.03722.0671.1891.1061.278
PLR0.0060.00140.2531.0061.0041.008
GPR0.1230.03512.2141.1311.0561.212
ER – early recurrence; BMI – body mass index; BCLC staging – Barcelona clinic liver cancer staging; WBC – white blood cell; RBC – red blood cell; HGB – hemoglobin; PLT – platelets; NEUT – neutrophil; LY – lymphocyte; AST – aspartate aminotransferase; ALT – alanine transaminase; TBIL – total bilirubin; ALB – albumin; GGT – gamma-glutamyl transpeptidase; AFP – alpha fetoprotein; NLR – neutrophil-to-lymphocyte ratio; PLR – platelet-to-lymphocyte ratio; GPR – the ratio of gamma-glutamyl transpeptidase to platelets.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750