22 March 2021 : Clinical Research
Heterotopic Ossification After Prestige-LP Cervical Disc Arthroplasty Is Related to Insufficient Sagittal Coverage of the Endplate By the Prosthesis
Shuai Xu1ABEF*, Yunsheng Ou1ABCDE, Xing Du1ABEF, Bin He1ACDEF, Yuanqiang Li1BCE, Haoyang Yu1CDEDOI: 10.12659/MSM.929890
Med Sci Monit 2021; 27:e929890
Table 2 Clinical and imaging features of the included patients.
| Index | HO (N=24) | No HO (n=49) | χ2/t value | P value |
|---|---|---|---|---|
| Male: Female (n) | 12: 12 | 30: 19 | 0.831a | 0.362 |
| Age (year) | 46.25±9.67 | 47.04±9.08 | 0.342 | 0.733 |
| BMI (kg/m) | 23.40±3.25 | 23.81±3.57 | 0.474 | 0.637 |
| Use NSAIDs: (yes/no) (n) | 11: 13 | 28: 21 | 0.828a | 0.363 |
| Single segment: double segment (n) | 17: 7 | 41: 8 | 1.627a | 0.202 |
| Follow-up time (months) | 20.71±10.32 | 23.96±10.47 | 1.252 | 0.764 |
| Nuchal ligament ossification: (yes/no) (n) | 7: 17 | 9: 40 | 1.098a | 0.295 |
| Intervertebral height/adjacent intervertebral height | 0.84±0.08 | 0.88±0.07 | 2.036 | 0.046 |
| Preoperative ROM of the replacement segment (°) | 5.84±1.09 | 7.73±1.22 | 6.423 | <0.001 |
| Postoperative ROM of the replacement segments (°) | 7.03±1.04 | 8.85±1.19 | 6.389 | <0.001 |
| The upper prosthesis-endplate sagittal distance (mm) | 3.69±0.90 | 1.88±0.54 | −10.706 | <0.001 |
| The lower prosthesis-endplate sagittal distance (mm) | 1.58±0.81 | 1.20±0.60 | −2.233 | 0.029 |
| HO – heterotopic ossification; NSAIDs – nonsteroidal anti-inflammatory drugs; ROM – range of motion. # Compared among the two groups: preoperative ROM of the replacement segment, postoperative ROM of the replacement segments, upper prosthesis-endplate sagittal distance ( | ||||






