03 May 2021>: Meta-Analysis
The Roles of Reduced Folate Carrier-1 (RFC1) A80G (rs1051266) Polymorphism in Congenital Heart Disease: A Meta-Analysis
Kang Yi 12ABCDEF* , Yu-Hu Ma 23ABCDEF* , Wei Wang 23BCF , Xin Zhang 24BCF , Jie Gao 23BCD , Shao-E He 25BCD , Xiao-Min Xu 23CDF , Meng Ji 23CDF , Wen-Fen Guo 6ADEG* , Tao You 12ABCDEFG*DOI: 10.12659/MSM.929911
Med Sci Monit 2021; 27:e929911
Table 1 Characteristics of included studies.
First author | Year | Country | Region | Genotyping method | Case type | Controls source | PHWE |
---|---|---|---|---|---|---|---|
Wang BJ []27 | 2013 | China | East Asian | SNaPShot multiple PCR | CHD | HB | 0.142 |
Shaw GM []19 | 2003 | USA | North America | PCR-RFLP | CHD | PB | 0.0085 |
Gong DX []28 | 2012 | China | East Asian | MALDI-ToF-MS | TOF, TGA | HB | 0.189 |
Pei LJ []29 | 2006 | China | East Asian | PCR-RFLP | CHD | PB | 0.9 |
Koshy T []30 | 2015 | India | South Asian | ABI 3730 automated sequencer | CTD | PB | 0.00036 |
Wang XK []18 | 2018 | China | East Asian | Taqman SNP Genotyping Assay | CTD | HB | 0.0000584 |
Pei LJ []29 | 2006 | China | East Asian | PCR-RFLP | CHD | PB | 0.601 |
CHD – congenital heart disease; HWE – Hardy Weinberge quilibrium; NA – notavailable; TGA – transposition of the great arteries; TOF – tetralogy of fallot; PB – population-based; HB – hospital-based; CTD – conotruncal heart defects. |