The Roles of Reduced Folate Carrier-1 (RFC1) A80G (rs1051266) Polymorphism in Congenital Heart Disease: A Meta-Analysis

Kang Yi; Yu-Hu Ma; Wei Wang; Xin Zhang; Jie Gao; Shao-E He; Xiao-Min Xu; Meng Ji; Wen-Fen Guo; Tao You

doi:10.12659/MSM.929911

03 May 2021 : Meta-Analysis

The Roles of Reduced Folate Carrier-1 (RFC1) A80G (rs1051266) Polymorphism in Congenital Heart Disease: A Meta-Analysis

Kang Yi^12ABCDEF, Yu-Hu Ma^23ABCDEF, Wei Wang^23BCF, Xin Zhang^24BCF, Jie Gao^34BCD, Shao-E He^25BCD, Xiao-Min Xu^23CDF, Meng Ji^23CDF, Wen-Fen Guo^6ADEG, Tao You^12ABCDEFG*

DOI: 10.12659/MSM.929911

Med Sci Monit 2021; 27:e929911

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Table 2 Genotype characteristics of included studies.

First author	Cases				Controls				Allele frequencies cases		Allele frequencies controls
First author	Total	GG	GA	AA	Total	GG	GA	AA	G	A	G	A

Wang BJ []²⁷	160	31	87	42	188	33	103	52	0.466	0.534	0.449	0.551
Shaw GM []¹⁹	163	47	90	26	239	75	99	65	0.564	0.436	0.521	0.479
Gong DX []²⁸	238	56	129	53	134	43	59	32	0.506	0.494	0.541	0.459
Pei LJ []²⁹	67	13	42	12	99	27	50	22	0.507	0.493	0.525	0.475
Koshy T []³⁰	96	39	30	27	100	48	30	22	0.5625	0.4375	0.63	0.37

Wang XK []¹⁸	193	68	69	56	234	102	82	50	0.531	0.469	0.611	0.389
Pei LJ []²⁹	65	12	39	14	100	31	47	22	0.485	0.515	0.545	0.455

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The Roles of Reduced Folate Carrier-1 (RFC1) A80G (rs1051266) Polymorphism in Congenital Heart Disease: A Meta-Analysis

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