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03 May 2021: Meta-Analysis

The Roles of Reduced Folate Carrier-1 (RFC1) A80G (rs1051266) Polymorphism in Congenital Heart Disease: A Meta-Analysis

Kang Yi 12ABCDEF* , Yu-Hu Ma 23ABCDEF* , Wei Wang 23BCF , Xin Zhang 24BCF , Jie Gao 23BCD , Shao-E He 25BCD , Xiao-Min Xu 23CDF , Meng Ji 23CDF , Wen-Fen Guo 6ADEG* , Tao You 12ABCDEFG*

DOI: 10.12659/MSM.929911

Med Sci Monit 2021; 27:e929911

Table 5 Meta-analysis of fetal reduced folate carrier-1 (RFC1) A80G polymorphism and maternal risk of congenital heart disease.

TypeOR (95%CI)zPTest of heterogeneityAnalysis model
GA VS GG1.44 [0.98, 2.11]1.860.06240.25Fixed-effects model
AA VS GG2.99 [1.06, 8.41]2.080.04720.06Random-effects model
GA+AA VS GG1.53 [1.08, 2.16]2.40.0200.44Fixed-effects model
AA VS GG+GA1.35 [0.92, 1.97]1.540.1200.33Fixed-effects model
A VS G1.36 [1.07, 1.71]2.560.0100.75Fixed-effects model

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750