03 May 2021 : Meta-Analysis
The Roles of Reduced Folate Carrier-1 (RFC1) A80G (rs1051266) Polymorphism in Congenital Heart Disease: A Meta-Analysis
Kang Yi12ABCDEF, Yu-Hu Ma23ABCDEF, Wei Wang23BCF, Xin Zhang24BCF, Jie Gao34BCD, Shao-E He25BCD, Xiao-Min Xu23CDF, Meng Ji23CDF, Wen-Fen Guo6ADEG, Tao You12ABCDEFG*DOI: 10.12659/MSM.929911
Med Sci Monit 2021; 27:e929911
Table 5 Meta-analysis of fetal reduced folate carrier-1 (RFC1) A80G polymorphism and maternal risk of congenital heart disease.
Type | OR (95%CI) | z | P | Test of heterogeneity | Analysis model | |
---|---|---|---|---|---|---|
I2 | p* | |||||
GA VS GG | 1.44 [0.98, 2.11] | 1.86 | 0.06 | 24 | 0.25 | Fixed-effects model |
AA VS GG | 2.99 [1.06, 8.41] | 2.08 | 0.04 | 72 | 0.06 | Random-effects model |
GA+AA VS GG | 1.53 [1.08, 2.16] | 2.4 | 0.02 | 0 | 0.44 | Fixed-effects model |
AA VS GG+GA | 1.35 [0.92, 1.97] | 1.54 | 0.12 | 0 | 0.33 | Fixed-effects model |
A VS G | 1.36 [1.07, 1.71] | 2.56 | 0.01 | 0 | 0.75 | Fixed-effects model |