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31 May 2021 : Clinical Research  

Association of High-Mobility Group Box 1 (HMGB1) Gene Polymorphisms with Susceptibility and Better Survival Prognosis in Chinese Han Neonatal Necrotizing Enterocolitis

Huiling Cao1ABCEF, Defeng Guo2CEF*

DOI: 10.12659/MSM.930015

Med Sci Monit 2021; 27:e930015

Table 3 Univariate analysis for factors that were related with the survival prognosis of necrotizing enterocolitis (NEC).

FactorsSurvival (n=197)Death (n=61)P value
Metabolic acidosis1535<0.001
Respiratory distress syndrome59250.108
Neonatal scleredema19140.007
Intestinal perforation924<0.001
Diffuse peritonitis2923<0.001
Thrombocytopenia2426<0.001
Leukocyte disorder65330.003
rs1360485 genotypes TC+CC869<0.001

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750