23 August 2021: Meta-Analysis
Periodontitis and Number of Teeth in the Risk of Coronary Heart Disease: An Updated Meta-Analysis
Shuting Gao 1BEF , Jinhui Tian 2A , Yiting Li 1CD , Tingjie Liu 1B , Ruiping Li 1C , Lan Yang 3FG* , Zhankui Xing 1AG*DOI: 10.12659/MSM.930112
Med Sci Monit 2021; 27:e930112
Table 2 Study characteristics.
| Reference | Sample size | Age range | Control group | Study area | Follow-up year | Periodontal condition/teeth number at baseline | CHD assessment |
|---|---|---|---|---|---|---|---|
| 20749 | 25–74 | No periodontitis | USA | 14 | Periodontitisgingivitisedentulous | CHD mortality and admission to hospital | |
| 44119 | 40–75male | No periodontitis32-25 | USA | 6 | Periodontitis32-25; 24-1716-11; 10-0 | Incidence of fatal and non-fatal MI and sudden death | |
| 16090 | 35–84 | No periodontitis | Canada | 23 | Periodontitisgingivitisedentulous | Risk of fatal CHD | |
| 8032 | 25–74 | No periodontitis32-25 | USA | 6 | Periodontitisgingivitis32-25; 24-17;16-11; 10-4 | Fatalities, hospitalization of CHD and revascularization | |
| 9962 | 25–54 | No periodontitis | USA | 21 | Periodontitisgingivitisedentulous | Hospital records for non-fatal events and death certificates for fatal events | |
| 22037 | 40–84male | No periodontitis | USA | 12.3 | Periodontitis | Nonfatal MI | |
| 100381 | 40–75 male30–55 female | 32-25 | USA | 12 | 32-25; 24-17;16-11; 10-0 | Symptomatic nonfatal MI, fatal CHD, or sudden death | |
| 15273 | >35 | No periodontitis | Sweden | 35 | Periodontitis | Coronary heart disease (ICD-9 codes 410–414) | |
| 7674 | 20–89 | No periodontitis>25 | Sweden | 12 | Periodontitis>25; 25-20;19-15; 14-10; | ICD mortality (ICD-8, ICD-9, and ICD-10) | |
| 3081 | 36–59 male | No periodontitis | Japan | 5 | Periodontitis | MI | |
| 8446 | 25–74 | 0–1 | Finland | 13 | 0–1; 2–45–8; 9–31; 32 | A history of myocardial infarction, revascularizations, or percutaneous transluminal coronary angioplasty | |
| 39863 | ≥45 female | No periodontitis | USA | 15.7 | Periodontitis | MI | |
| The sample size includes the original population, not excluding loss. CHD – coronary heart disease; MI – myocardial infarction; ICD – International Classification of Disease. | |||||||