Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

23 August 2021: Meta-Analysis

Periodontitis and Number of Teeth in the Risk of Coronary Heart Disease: An Updated Meta-Analysis

Shuting Gao 1BEF , Jinhui Tian 2A , Yiting Li 1CD , Tingjie Liu 1B , Ruiping Li 1C , Lan Yang 3FG* , Zhankui Xing 1AG*

DOI: 10.12659/MSM.930112

Med Sci Monit 2021; 27:e930112

Table 3 Hazard ratio (HR) or risk ratio (RR) of included studies sorted by adjustment factors in meta-analysis with subgroup as periodontal condition.

Gingivitis1.050.88–1.26Age, sex, race, education, poverty, alcohol, systolic blood pressure, marital status, BMI, smoking, physical activity, and cholesterol
PD1.040.97–1.25Age and smoking
Mild gingivitis1.450.85–2.48Age and sex
Severe gingivitis1.821.09–3.06
Edentulous1.891.18–3.04Serum total cholesterol, diabetes status, smoking status, province of residence, hypertensive status, age and sex
Mild gingivitis1.540.89–2.67
Severe gingivitis2.151.25–3.72
Gingivitis0.990.77–1.28Age, age squared, sex, race, education, poverty Index, marital status, interaction term for marital status and sex
Gingivitis1.030.87–1.21several well-established CVD risk factors and demographic variables
PD1.010.87–1.17Age, aspirin, cigarette, smoking, alcohol, history of hypertension, BMI, diabetes, physical activity, history of MI and angina*
PD1.41.1–1.6Age, sex, education, smoking, diabetes, number of siblings, hypertension, and BMI
Moderate PD0.730.26–2.01Age, gender, smoking
severe PD0.780.27–2.21
2.260.84–6.02Age, smoking, diabetes, hypertension and BMI
# The multivariate model includes age (continuous); body mass index (BMI) (5 categories); exercise (5 categories); smoking habits (current smoker [number of cigarettes smoked: 1–14, 15–24, 25+], former smoker, or never smoked); alcohol consumption (7 categories); family history of myocardial infarction (MI) before 60 years of age; vitamin E (5 categories).
$ Multivariate model includes demographics and socioeconomic status: age, sex, race, poverty index, and cardiovascular risk factors (smoking, cigarettes, blood pressure, cholesterol, diabetes, height, physical activity).
* Age (years), aspirin and beta-carotene treatment assignment, cigarette smoking, alcohol use, history of hypertension (systolic blood pressure ≥160 mmHg, diastolic blood pressure ≥95 mmHg or history of treatment for high blood pressure), BMI, reported history of diabetes, physical activity (reported vigorous exercise once per week or more), parental history of myocardial infarction (MI) and history of angina.
& Multivariate model includes age, race/ethnicity, BMI, education, smoking, diabetes, hypertension, family history of MI, physical activities, and C-reactive protein.
BMI – body mass index; HR/RR – hazard ratio/relative risk; CI – confidence interval; MI – myocardial infarction.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750