24 August 2021>: Clinical Research
Different Doses of Nalbuphine Combined with Dexmedetomidine in Laparoscopic Oophorocystectomy
Xiaofen Liu ABCDEF , Jie Song BCDF , Yang Zhang BCDF , Ye Zhang BCDF , Xianwen Hu CDFG*DOI: 10.12659/MSM.930197
Med Sci Monit 2021; 27:e930197
Table 2 VAS scores and PCIA pressing times within 48 h after surgery in all patients.
Variables | LND, n=55 | MND n=54 | HND, n=55 | Control, n=55 | P value | |
---|---|---|---|---|---|---|
Rest | VAS at 2 h | 3.24±0.89c | 3.03±0.59c | 2.61±0.49a | 4.24±0.93a | |
VAS at 8 h | 3.00±0.60b | 2.49±0.31a | 2.14±0.32a | 3.80±0.78a | ||
VAS at 12 h | 2.07±0.52c | 1.93±0.36c | 1.50±0.33a | 2.96±0.71a | ||
VAS at 24 h | 1.51±0.28b | 1.24±0.47a | 1.05±0.33a | 2.28±0.45a | ||
VAS at 48 h | 1.10±0.32 | 1.08±0.33 | 1.05±0.31 | 1.05±0.32 | 0.849 | |
Cough | VAS at 2 h | 4.44±0.83b | 3.87±0.64a | 3.20±0.57a | 5.14±1.16a | |
VAS at 8 h | 4.12±0.62b | 3.37±0.74a | 2.74±0.72a | 4.53±0.94a | ||
VAS at 12 h | 2.93±0.64b | 2.57±0.61a | 2.18±0.50a | 3.55±0.85a | ||
VAS at 24 h | 2.02±0.54b | 1.43±0.51a | 1.29±0.52a | 2.84±0.52a | ||
VAS at 48 h | 1.45±0.35 | 1.44±0.34 | 1.46±0.37 | 1.51±0.38 | 0.799 | |
PCIA | 2.18±1.09c | 2.16±0.90c | 1.57±0.49a | 3.16±1.31a | ||
a b c d LND – low-dose nalbuphine and dexmedetomidine; MDN – middle-dose nalbuphine and dexmedetomidine; HND – high-dose nalbuphine and dexmedetomidine; PCIA – patient-controlled intravenous analgesia pump. |