09 July 2021 : Clinical Research
Secondary Immunodeficiency and Hypogammaglobulinemia with IgG Levels of <5 g/L in Patients with Multiple Myeloma: A Retrospective Study Between 2012 and 2020 at a University Hospital in China
Chunmei Ye12BCEF, Weiwei Chen3EF, Qi Gao12B, Yanxia Chen4B, Xiaolu Song5B, Sujie Zheng2C, Jinlin Liu2AEG*DOI: 10.12659/MSM.930241
Med Sci Monit 2021; 27:e930241
Table 1 Past history of infection of multiple myeloma patients with and without secondary immunodeficiency.
| IgG <5 g/L (n=45) | IgG ≥5 g/L (n=103) | |
|---|---|---|
| Infection times (per year) | ||
| 0 | 4 (8.89) | 33 (32.00) |
| 1 | 30 (66.67) | 56 (54.37) |
| 2 | 11 (24.44) | 18 (17.48) |
| 3 | 6 (13.33) | 4 (3.88) |
| 4 | 3 (6.67) | 2 (1.94) |
| 5 | 2 (4.44) | 2 (1.94) |
| Localization of infection | ||
| Lung | 31 (68.89) | 57 (55.34) |
| Upper respiratory tract | 8 (17.78) | 11 (10.67) |
| Genitourinary | 5 (11.11) | 0 (0.00) |
| Gingiva | 2 (4.44) | 0 (0.00) |
| Others | 13 (28.89) | 9 (0.87) |
| Type of infection | ||
| Bacteria | 42 (93.33) | 82 (79.62) |
| Proven fungal | 2 (4.44) | 4 (3.88) |
| Virus | 5 (11.11) | 6 (5.83) |
| Probable fungal | 3 (6.67) | 5 (4.85) |
| All data are presented with no. (%). | ||