Secondary Immunodeficiency and Hypogammaglobulinemia with IgG Levels of <5 g/L in Patients with Multiple Myeloma: A Retrospective Study Between 2012 and 2020 at a University Hospital in China

09 July 2021 : Clinical Research

Chunmei Ye^12BCEF, Weiwei Chen^3EF, Qi Gao^12B, Yanxia Chen^4B, Xiaolu Song^5B, Sujie Zheng^2C, Jinlin Liu^2AEG*

DOI: 10.12659/MSM.930241

Med Sci Monit 2021; 27:e930241

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Table 6 Multivariate analysis of secondary immunodeficiency in patients with multiple myeloma (MM) and matched MM patients.

Variable	Hazard ratio	95% Confidence interval	P value
Hypogammaglobulinemia (IgG <5 g/L vs IgG ≥5 g/L)	0.335	0.197–0.571	<0.001
Sex (Male vs Female)	0.516	0.288–0.922	0.026
Albumin (≤3.5 g/dL vs >3.5 g/dL) (146 cases available)	0.443	0.241–0.815	0.009

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