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18 June 2021 : Clinical Research  

Relationship of Bone Status with Serum Uric Acid and Bilirubin in Men with Type 2 Diabetes: A Cross-Sectional Study

Yang Wu1ABCDEF, Shoukui Xiang1BCDE, Xiaohong Jiang1B, Long Wang1BF, Kun Wang2AG, Fei Hua1AG*

DOI: 10.12659/MSM.930410

Med Sci Monit 2021; 27:e930410

Table 1 Characteristics of the participants.

CharacteristicsAll (n=631)T-score ≥-1 (n=257)T-score <−1 (n=374)P
Age (years)57.3±12.056.6±11.957.8±12.10.217
BMI (kg/m)24.9±3.626.0±4.024.2±3.10.000
Diabetes duration (years)8.4±7.88.4±7.58.4±8.10.996
HbA1c (%)9.7±2.49.6±2.29.7±2.50.611
FBG (mmoL/L)9.1±3.29.1±3.29.1±3.30.968
Insulin or analog use, n (%)235 (37.2)102 (16.2)133 (21.1)0.475
Hypertension, (n%)371 (58.8)163 (25.8)208 (33.0)0.050
Current smoker, n (%)296 (46.9)112 (17.7)184 (29.2)0.165
Drinking habits, n (%)211 (33.4)93 (14.7)118 (18.7)0.378
Total cholesterol (nmoL/L)4.5±1.24.5±1.34.4±1.10.434
Triglycerides (nmoL/L)2.4±2.42.4±2.22.3±2.40.633
HDL (nmoL/L)1.0±0.21.0±0.21.0±0.20.928
LDL (nmoL/L)2.6±0.92.6±0.82.5±0.80.943
Albumin39.7±4.939.8±4.039.6±5.50.611
Creatinine (μmoL/L)76.4±14.777.8±14.175.4±15.10.043
Uric acid (μmoL/)323.7±84.4339.9±86.9312.7±80.90.000
TBIL (mmol/l)11.7±3.912.1±4.111.5±3.80.079
25(OH) D3 (ng/ml)18.6±7.919.4±8.218.1±7.70.146
Calcium (mmol/l)2.3±0.12.3±0.12.3±0.10.336
Phosphorus (mmol/l)1.2±0.21.2±0.21.2±0.20.445
TH BMD−0.5±0.80.1±0.6−0.9±0.70.000
FN BMD−1.1±0.9−0.5±0.7−1.5±0.70.000
LV BMD−0.8±1,30.2±0.9−1.5±1.00.000
OC (ng/ml)11.4±4.410.6±3.712.0±4.70.000
PINP (ng/ml)37.8±15.235.1±13.639.7±16.00.000
CTX (pg/ml)415.0±224.1366.8±198.7448.1±234.60.000
PTH (pg/ml)36.5±14.136.6±14.636.5±13.80.913
BMI – body index; HbA1c – glycosylated hemoglobin; FBG – fasting blood glucose; HDL – high-density lipoprotein; LDL – low-density lipoprotein; TBIL – total bilirubin; TH – total hip; FN – femoral neck; LV – lumbar vertebral; BMD – bone mineral density; OC – osteocalcin; PINP – amino-terminal propeptide of type I procollagen; CTX – type I collagen carboxy-terminal peptide; PTH – parathyroid hormone.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750