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19 May 2021: Animal Study

Pretreatment with Propofol Reduces Pulmonary Injury in a Pig Model of Intestinal Ischemia-Reperfusion via Suppressing the High-Mobility Group Box 1 Protein (HMGB1)/Toll-Like Receptor 4 (TLR4)/Protein Kinase R (PKR) Signaling Pathway

Wen-yu Bian 1BC* , Ya-ping Chen 2DF* , Bo Xu 3AE* , Jun Tang 4AE*

DOI: 10.12659/MSM.930478

Med Sci Monit 2021; 27:e930478

Table 1 Results of arterial blood gas analysis.

GroupsPaO2 (mmHg)pHDA-aO2 (mmHg)
Sham group273±137.47±0.01024±4
IIR+NS group214±7* 7.33±0.155* 62±6*
IIR+P group255±9# 7.45±0.008# 44±5#
Data are expressed as mean±SD, n=8.
PaO – arterial oxygen partial pressure; DA-aO2 – alveolar-arterial oxygen pressure difference.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750