13 August 2021 : Clinical Research
Brain Functional Connectivity Changes in Patients with Acute Eye Pain: A Resting-State Functional Magnetic Resonance Imaging (fMRI) Study
Yan-Chang Yang1ABCEF*, Guo-Qian Cai2AB, Qi-Chen Yang3CD, Biao Li4DF, Qian-Min Ge4EF, Qiu-Yu Li4DF, Wen-Qing Shi4F, You-Lan Min4F, Rong-Bin Liang5F, Yi Shao5ACGDOI: 10.12659/MSM.930588
Med Sci Monit 2021; 27:e930588
Table 3 Significant differences in degree centrality between different brain regions of eye pain and healthy control groups.
| Brain areas | MNI coordinates | EP and HC | ROI | ||||
|---|---|---|---|---|---|---|---|
| X | Y | Z | BA | Peak voxels | T value | ||
| EP>HC | |||||||
| Right cerebellum posterior lobe | 30 | −69 | −54 | 94 | 4.4116 | 1 | |
| Left cerebellum posterior lobe | −33 | −66 | −54 | 48 | 4.5262 | 2 | |
| Left inferior temporal gyrus | −36 | −15 | −24 | 20 | 45 | 3.7357 | 4 |
| Left inferior parietal lobule | −36 | −63 | 45 | 40 | 158 | 3.8899 | 5 |
| Left precuneus | −6 | −75 | 48 | 7 | 40 | 3.6715 | 6 |
| EP | |||||||
| Left limbic lobe | −24 | 9 | −30 | 29 | 41 | −3.5969 | 3 |
| The statistical threshold was set at the voxel level, and multiple comparisons were made using the Gaussian random field (GRF) theory (z>2.3, | |||||||






