13 August 2021 : Clinical Research
Brain Functional Connectivity Changes in Patients with Acute Eye Pain: A Resting-State Functional Magnetic Resonance Imaging (fMRI) Study
Yan-Chang Yang1ABCEF*, Guo-Qian Cai2AB, Qi-Chen Yang3CD, Biao Li4DF, Qian-Min Ge4EF, Qiu-Yu Li4DF, Wen-Qing Shi4F, You-Lan Min4F, Rong-Bin Liang5F, Yi Shao5ACGDOI: 10.12659/MSM.930588
Med Sci Monit 2021; 27:e930588
Table 5 DC method applied in ophthalmological diseases.
| Author | Year | Disease | Increased DC | Decreased DC |
|---|---|---|---|---|
| Wang et al []51 | 2017 | Acute unilateral open globe injury | Bilateral primary visual cortex and left PCUN | Right insula, left insula, RIPL/SMG, IPL/SMG, right supplementary motor area and right postcentral gyrus |
| Tan et al []52 | 2017 | Adult comitant exotropia strabismus | Right superior temporal gyrus, bilateral anterior cingulate, right superior temporal gyrus, and left inferior parietal lobule | Right cerebellum posterior lobe, right inferior frontal gyrus, right middle frontal gyrus and right superior parietal lobule/primary somatosensory cortex |
| Hu et al []53 | 2018 | High myopia | Right cerebellum posterior lobe, left precentral gyrus/postcentral gyrus, and right middle cingulate gyrus | Right inferior frontal gyrus/insula, right middle frontal gyrus, and right supramarginal/inferior parietal lobule |
| Zhu et al []54 | 2019 | Trigeminal neuralgia | Right lingual gyrus, right postcentral gyrus, left paracentral lobule, and bilateral inferior cerebellum | / |
| Wang et al []55 | 2019 | Diabetic nephropathy and retinopathy | BP | RITG, LSG |
| Liu et al []56 | 2020 | Exophthalmos of primary hyperthyroidism | / | Cerebellum posterior lobe |
| Zhang et al []57 | 2020 | Ophthalmectomy | Left cerebellum posterior lobe, left middle frontal gyrus1, right supramarginal gyrus, left middle frontal gyrus, right middle frontal gyrus | Left lingual gyrus, bilateral lingual lobe, left cingulate gyrus |
| DC – degree centrality; PCUN – precuneus; RIPL – right inferior parietal lobule; SMG – supramarginal gyrus; IPL – inferior parietal lobule; BP – bilateral precuneus; RITG – right inferior temporal gyrus; LSG – left subcallosal gyrus regions. | ||||






