Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students

Jing Zhang; Mengyi Yang; Pengfei Luan; Wei Jia; Qiujun Liu; Zhanbing Ma; Jie Dang; Hong Lu; Qian Ma; Yanfeng Wang; Chunlan Mu; Zhenghao Huo

doi:10.12659/MSM.930591

16 March 2021 : Database Analysis

Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students

Jing Zhang^12ABCDEF, Mengyi Yang^1B, Pengfei Luan^1B, Wei Jia^1B, Qiujun Liu^1B, Zhanbing Ma^1A, Jie Dang^1A, Hong Lu^1A, Qian Ma^1B, Yanfeng Wang^1B, Chunlan Mu^1B, Zhenghao Huo^13AG*

DOI: 10.12659/MSM.930591

Med Sci Monit 2021; 27:e930591

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Table 5 The association between CYP17A1 SNPs and 2D: 4D under different haplotypes for men and women.

rs17115149-rs1004467-rs2486758		L2D: 4D			R2D: 4D			DR-L
rs17115149-rs1004467-rs2486758		Mean±SD	F	p	Mean±SD	F	p	Mean±SD	F	p
Total	G-A-T	0.9639±0.0331	1.116	0.341	0.962±0.0328	1.790	0.147	−0.0019±0.0272	0.239	0.869
	G-G-T	0.9618±0.0338			0.9589±0.0331			−0.0030±0.0275
	G-A-C	0.9662±0.0370			0.9644±0.0320			−0.0018±0.0292
	T-A-T	0.9657±0.0305			0.9622±0.0355			−0.0035±0.0290
Male	G-A-T	0.9605±0.0343	2.135	0.094	0.9593±0.0321	4.382	0.005^**	−0.0013±0.0277	0.389	0.761
	G-G-T	0.9577±0.0374			0.9544±0.0332			−0.0034±0.0275
	G-A-C	0.9666±0.0404			0.9659±0.0313			−0.0006±0.0307
	T-A-T	0.9662±0.0257			0.9657±0.0339			−0.0004±0.0279
Female	G-A-T	0.9673±0.0316	0.197	0.898	0.9648±0.0333	0.645	0.586	−0.0025±0.0268	0.396	0.756
	G-G-T	0.9656±0.0296			0.9630±0.0326			−0.0026±0.0275
	G-A-C	0.9659±0.0337			0.9630±0.0327			−0.0028±0.0278
	T-A-T	0.9652±0.0351			0.9586±0.0371			−0.0066±0.0300
^** SNPs – single-nucleotide polymorphisms; 2D: 4D – second-to-fourth digit ratio.

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Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students

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