19 March 2021 : Clinical Research
Association Between Body Mass Index and Thyroid Function in Euthyroid Chinese Adults
Jing Fu1ACE, Lin Zhang1BDF, Yu An1C, Yan Duan1B, Jia Liu1ADE*, Guang Wang12AFDOI: 10.12659/MSM.930865
Med Sci Monit 2021; 27:e930865
Table 3 Logistic regression analyses of the risk of higher levels of indices for thyroid function.
| TSH | FT3 | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Model 1 | ||||||
| Normal weight | Ref | Ref | ||||
| Overweight | 1.151 | 0.932–1.421 | 0.192 | 1.279* | 1.035–1.581 | 0.022 |
| Obesity | 1.624** | 1.145–2.302 | 0.007 | 1.778** | 1.254–2.521 | 0.001 |
| Model 2 | ||||||
| Normal weight | Ref | Ref | ||||
| Overweight | 1.138 | 0.921–1.407 | 0.232 | 1.350** | 1.082–1.684 | 0.008 |
| Obesity | 1.609** | 1.133–2.285 | 0.008 | 1.871** | 1.294–2.707 | 0.001 |
| Model 1 | ||||||
| Normal weight | Ref | Ref | ||||
| Overweight | 0.955 | 0.774–1.179 | 0.670 | 1.390** | 1.125–1.718 | 0.002 |
| Obesity | 0.804 | 0.568–1.137 | 0.217 | 2.080** | 1.454–2.976 | <0.001 |
| Model 2 | ||||||
| Normal weight | Ref | Ref | ||||
| Overweight | 0.972 | 0.785–1.205 | 0.799 | 1.415** | 1.144–1.750 | 0.001 |
| Obesity | 0.793 | 0.556–1.129 | 0.198 | 2.118** | 1.478–3.037 | <0.001 |
| TSH – thyroid-stimulating hormone; FT3 – free triiodothyronine; FT4 – free thyroxine. Normal weight: body mass index (BMI) 18.5 to 23.9 kg/m. Overweight: BMI 24.0 to 27.9 kg/m. Obese: BMI ≥28 kg/m. The dividing point for serum thyrotropin (TSH) was 1.52 mIU/L; for FT3, it was 5.33 pmol/L; for FT4, it was 16.36 pmol/L; and for FT3/FT4, it was 0.33. Model 1: Odds ratio (OR) and 95% confidence interval (CI) were calculated using logistic regression models without adjustment for variables. Model 2: OR and 95% CI were calculated using logistic regression models and adjusted for age and sex. * ** | ||||||