10 July 2021 : Database Analysis
Outcomes of Targeted Temperature Management for In-Hospital and Out-Of-Hospital Cardiac Arrest: A Matched Case-Control Study Using the National Database of Taiwan Network of Targeted Temperature Management for Cardiac Arrest (TIMECARD) Registry
Yu-san Chien12BCDEF, Min-Shan Tsai3B, Chien-Hua Huang3A, Chih-Hung Lai4AB, Wei-Chun Huang5A, Lung Chan
6AB, Li-Kuo Kuo12ADF*
DOI: 10.12659/MSM.931203
Med Sci Monit 2021; 27:e931203
Table 2 Resuscitation-associated parameters and characteristics after return of spontaneous circulation of IHCA and OHCA patients receiving targeted temperature management.
| IHCA | N=103 | OHCA | N=103 | P value | |
|---|---|---|---|---|---|
| Time to initiation of CPR (min), mean (SD) | 1.5 | 5.6 | 10.0 | 12.0 | 0.000 |
| Witnessed collapse, N (%) | 98 | 95.2% | 76 | 73.8% | 0.000 |
| Bystander CPR, N (%) | 88 | 85.4% | 60 | 58.3% | 0.000 |
| Initial shockable rhythm, N (%) | 28 | 27.2% | 31 | 30.1% | 0.644 |
| Presumed cardiac collapse, N (%) | 46 | 44.7% | 53 | 51.5% | 0.329 |
| Use of epinephrine, N (%) | 97 | 94.2% | 89 | 86.4% | 0.098 |
| Dose of epinephrine, mg, mean (SD) | 4.5 | 4.8 | 3.5 | 3.1 | 0.076 |
| Use of anti-arrhythmia, N (%) | 17 | 16.5% | 15 | 14.6% | 0.700 |
| Use of NaHCO, N (%) | 33 | 32% | 33 | 32% | 1.000 |
| Use of calcium, N (%) | 14 | 13.6% | 8 | 7.8% | 0.259 |
| Use of ECMO, N (%) | 12 | 11.7% | 8 | 7.8% | 0.481 |
| CPR duration (min), mean (SD) | 16.6 | 16.8 | 25.8 | 17.4 | 0.000 |
| Heart rate (bpm), mean (SD) | 107.2 | 27.9 | 106.0 | 30.3 | 0.756 |
| SBP (mmHg), mean (SD) | 124.1 | 27.9 | 140.7 | 44.7 | 0.011 |
| DBP (mmHg), mean (SD) | 70.4 | 26.9 | 81.4 | 32.2 | 0.009 |
| MAP (mmHg), mean (SD) | 88.3 | 32.1 | 101.1 | 34.0 | 0.006 |
| BT (°C), mean (SD) | 36.4 | 1.3 | 35.9 | 1.6 | 0.008 |
| Best motor, mean (SD) | 1.4 | 0.9 | 1.4 | 1.0 | 0.667 |
| Brain CT, N (%) | 70 | 68.0% | 89 | 86.4% | 0.002 |
| Coronary angiography, N (%) | 22 | 21.4% | 33 | 32.0% | 0.083 |
| IHCA – in-hospital cardiac arrest; OHCA – out-of-hospital cardiac arrest; SD – standard deviation; ECMO – extracorporeal membrane oxygenation; ROSC – return of spontaneous circulation; CPR – cardiopulmonary resuscitation; SBP – systolic blood pressure; DBP – diastolic blood pressure; MAP – mean arterial pressure; BT – body temperature; CT – computed tomography. | |||||