Outcomes of Targeted Temperature Management for In-Hospital and Out-Of-Hospital Cardiac Arrest: A Matched Case-Control Study Using the National Database of Taiwan Network of Targeted Temperature Management for Cardiac Arrest (TIMECARD) Registry

10 July 2021 : Database Analysis

Yu-san Chien^12BCDEF, Min-Shan Tsai^3B, Chien-Hua Huang^3A, Chih-Hung Lai^4AB, Wei-Chun Huang^5A, Lung Chan

^6AB, Li-Kuo Kuo^12ADF*

DOI: 10.12659/MSM.931203

Med Sci Monit 2021; 27:e931203

Background Material and Methods Results Discussion Conclusions References

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Table 4A Predictors of survival to hospital discharge among patients receiving targeted temperature control in this cohort.

	Single-variate analysis				Multivariate analysis
	OR	95% CI		P value	OR	95% CI		P value
Pre-arrest CPC	0.776	0.643	0.936	0.008	0.546	0.342	0.871	0.011
Pre-arrest CCI	0.933	0.882	0.987	0.016	0.503	0.267	0.945	0.033
Initial shockable rhythm	1.626	1.166	2.268	0.004	3.145	1.484	6.667	0.003
Use of epinephrine during CPR	0.691	0.516	0.926	0.013
Use of NaHCO during CPR	0.500	0.300	0.834	0.008
Use of calcium during CPR	0.375	0.147	0.958	0.040
CPR duration ≥20 minutes	0.536	0.344	0.835	0.006	0.495	0.260	0.943	0.033
HR at ROSC ≥100 bpm	0.671	0.467	0.964	0.031	0.512	0.267	0.981	0.044
SBP at ROSC ≤120 mmHg	0.400	0.254	0.630	0.000	0.424	0.231	0.777	0.006
BT at ROSC ≤36°C	0.621	0.410	0.941	0.025
Time from ROSC to initiation of TTM ≥8 hours	0.391	0.181	0.846	0.017
Targeted temperature, °C	0.991	0.983	0.999	0.036
Time to normothermia during rewarm phase of TTM, hours	0.989	0.978	1.000	0.049
New arrhythmia during TTM	0.492	0.315	0.767	0.002	0.503	0.267	0.945	0.033
OR – odds ratio; CPC – cerebral performance category; CCI – Charlson comorbidity index; CPR – cardiopulmonary resuscitation; HR – heart rate; SBP – systolic blood pressure; BT – body temperature; TTM – targeted temperature management.

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