Intermittent Theta Burst Stimulation (iTBS) for Treatment of Chronic Post-Stroke Aphasia: Results of a Pilot Randomized, Double-Blind, Sham-Controlled Trial

Jerzy P. Szaflarski; Rodolphe Nenert; Jane B. Allendorfer; Amber N. Martin; Amy W. Amara; Joseph C. Griffis; Aimee Dietz; Victor W. Mark; Victor W. Sung; Harrison C. Walker; Xiaohua Zhou; Christopher J. Lindsell

doi:10.12659/MSM.931468

29 June 2021 : Clinical Research

Intermittent Theta Burst Stimulation (iTBS) for Treatment of Chronic Post-Stroke Aphasia: Results of a Pilot Randomized, Double-Blind, Sham-Controlled Trial

Jerzy P. Szaflarski^12ABDEFG*, Rodolphe Nenert^1BCDE, Jane B. Allendorfer^13BE, Amber N. Martin^1BE, Amy W. Amara^13BE, Joseph C. Griffis^14BE, Aimee Dietz^5AE, Victor W. Mark^146DE, Victor W. Sung^1BE, Harrison C. Walker^16BE, Xiaohua Zhou^6BE, Christopher J. Lindsell^7ACE

DOI: 10.12659/MSM.931468

Med Sci Monit 2021; 27:e931468

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Table 3 Main peak coordinates of paired t tests on general linear model analysis results included in Figure 4. Significant differences in cortical activity were found for Group 3 (G3), between pre-treatment and post-treatment (t4 >t1) and for the combined group (G1–3) between pre-treatment and 3-month follow-up (t1 >t5). Table shows all local maxima separated by more than 1 mm.

	Region Label	t-value	MNI coordinates
	Region Label	t-value	x	y	z
G3	Right Lingual gyrus	14.286	10	−64	−2
		10.971	10	−62	4
		9.701	14	−58	−8
		6.093	18	−52	−10
	Temporal_Mid_L	4.853	−50	−10	−20
	Temporal_Mid_L	4.629	−56	−14	−24
G1–3	Temporal_Mid_L	4.562	−54	−12	−22
	Frontal_Med_Orb_R	6.259	12	40	−2
	Frontal_Med_Orb_R	6.131	14	38	−4
	Frontal_Med_Orb_R	6.089	12	44	−4

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Intermittent Theta Burst Stimulation (iTBS) for Treatment of Chronic Post-Stroke Aphasia: Results of a Pilot Randomized, Double-Blind, Sham-Controlled Trial

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