10 December 2021 : Clinical Research
Development and Validation of a Random Forest Risk Prediction Pneumothorax Model in Percutaneous Transthoracic Needle Biopsy
Hong Lin Wu1ABCDEF, Gao Wu Yan2ADF, Li Cheng Lei3BC, Yong Du4AD, Xiang Ke Niu1DF, Tao Peng1FG*DOI: 10.12659/MSM.932137
Med Sci Monit 2021; 27:e932137
Table 2 Characteristics of validation data.
| Risk factors | N=97 | P value | |
|---|---|---|---|
| Pneumothorax (n=54) | Non-pneumothorax (n=43) | ||
| Patients’ characteristics | |||
| Age (years), Mean±SD | 63.3±11.1 | 62.1±13.1 | 0.654 |
| Gender(number), Male/Female | 31 (57.4%)/23 (42.6%) | 31 (72.1%)/12 (27.9%) | 0.135 |
| Lesion characteristics | |||
| Lesion size (mm), Mean±SD | 24.4±14.3 | 34.2±20.9 | 0.026 |
| Lesion depth (mm), Mean±SD | 6.7±10.5 | 2.6±4.6 | 0.037 |
| Lesion location (number), upper lobe (left lung)/lower lobe (left lung)/upper lobe (right lung)/middle lobe (right lung)/lower lobe (right lung) | 8 (14.8%)/9 (16.7%)/ 9 (16.7%)/8 (14.8%)/20 (37.0%) | 10 (23.3%)/11 (25.6%)/ 12 (27.9%)/3 (7.0%)/7 (16.3%) | 0.083 |
| Cavity inside the lesion (number), yes | 12 (22.2%) | 2 (4.7%) | 0.014 |
| Emphysema/bullae (number), yes | 7 (13.0%) | 9 (20.9%) | 0.294 |
| Pneumonitis (number), yes | 36 (66.7%) | 28 (65.1%) | 0.873 |
| Procedure characteristics | |||
| Length of the aerated lung traversed (mm), Mean±SD | 14.2±16.3 | 9.9±12.4 | 0.186 |
| Angle of pleural puncture (°), Mean±SD | 62.0±16.3 | 62.1±17.8 | 1.000 |
| Procedure time (min.), Mean±SD | 8.3±4.9 | 8.0±4.0 | 0.997 |
| Biopsy position (number), supine/prone | 20 (37.0%)/34 (63.0%) | 16 (37.2%)/27 (62.8%) | 0.986 |
| Crossing of pleural indentation (number), yes | 11 (20.4%) | 7 (16.3%) | 0.607 |
| Crossing the interlobar fissure (number), yes | 8 (14.8%) | 2 (4.7%) | 0.177 |
| Number of biopsy (number), 1/2/3 | 44 (81.5%)/9 (16.7%)/1 (1.9%) | 40 (93.0%)/3 (7.0%)/0 (0%) | 0.217 |






