07 August 2021: Clinical Research
A Retrospective Study of 268 Patients with SARS-CoV-2 Infection to Evaluate the Association Between Blood Glucose and Severity of COVID-19 Pneumonia and Patient Mortality
Yaoyao Sun 12CDE* , Nan Jiang 1ABD* , Zhijun Li 2CD , Xinwei Li 2DF , Bo Yang 3B , Daoyuan Si 4D , Piyong Ma 5BF , Jinnan Zhang 6BF , Ningning Jia 2EF , Mengdi Jin 2E , Yang He 2C , Xingyao Cui 2D , Tianji Liu 1AB* , Qiong Yu 2ABCDF*DOI: 10.12659/MSM.932156
Med Sci Monit 2021; 27:e932156
Table 1 The baseline characteristics of patients with COVID-19 (n, interquartile range, or percentage).
| Characteristics | Total (n=268) | Severe (n=96) | Non-severe (n=172) | P |
|---|---|---|---|---|
| Age, years | 57.75 (67.00, 73.00) | 70.00 (64.00, 76.75) | 65.00 (54.00, 72.00) | |
| Sex | 0.036 | |||
| Male | 139 (51.9) | 58 (60.4) | 81 (47.1) | |
| Female | 129 (48.1) | 38 (39.6) | 91 (52.9) | |
| Comorbidities | ||||
| Hypertension | 43/109 (39.4) | 27/69 (39.1) | 16/40 (40.0) | 0.929 |
| Diabetes | 21/109 (19.3) | 17/69 (24.6) | 4/40 (10.0) | 0.062 |
| Cardiovascular disease | 12/109 (11.0) | 8/69 (11.6) | 4/40 (10.0) | 1.000 |
| Chronic kidney disease | 1/109 (0.9) | 1/69 (1.4) | 0/40 (0.0) | 1.000 |
| Chronic liver disease | 1/109 (0.9) | 1/69 (1.4) | 0/40 (0.0) | 1.000 |
| Chronic obstructive pulmonary disease | 3/109 (2.8) | 2/69 (2.9) | 1/40 (2.5) | 1.000 |
| Blood glucose, mmol/L | 6.20 (5.28, 8.14) | 7.42 (6.02, 10.55) | 5.72 (5.12, 6.89) | |
| Leukocyte count, ×10/L | 6.17 (4.80, 8.99) | 9.26 (6.03, 12.35) | 5.64 (4.53, 6.98) | |
| Neutrophil count, ×10/L | 4.37 (3.13, 7.42) | 7.94 (4.55, 11.91) | 3.81 (2.61, 4.78) | |
| Lymphocyte count, ×10/L | 0.97 (0.65, 1.42) | 0.64 (0.45, 0.89) | 1.22 (0.85, 1.60) | |
| ALT, U/L | 24.50 (16.00, 41.00) | 29.00 (19.00, 42.75) | 23.00 (14.00, 40.00) | 0.021 |
| AST, U/L | 27.00 (19.00, 45.00) | 41.00 (25.25, 62.00) | 23.50 (18.00, 34.00) | |
| LDH, U/L | 290.00 (225.25, 455.00) | 480.00 (333.25, 635.50) | 252.50 (209.75, 328.75) | |
| Total bilirubin, μmol/L | 10.50 (7.30, 14.60) | 13.10 (9.53, 18.20) | 9.50 (7.00, 13.00) | |
| Creatinine, μmol/L | 74.50 (60.25, 92.75) | 85.50 (68.25, 109.75) | 70.00 (59.00, 84.00) | |
| Duration of hospitalization, days | 20.00 (9.25, 27.00) | 16.00 (5.25, 28.00) | 21.00 (12.25, 27.00) | 0.058 |
| ALT – alanine aminotransferase; AST – aspartate transaminase; LDH – lactic dehydrogenase | ||||