Expression of Interleukin-17, Tumor Necrosis Factor-Alpha, and Matrix Metalloproteinase-8 in Patients with Chronic Peri-Implant Mucositis

Darius Gleiznys; Albertas Kriauciunas; Julius Maminskas; Arturas Stumbras; Dalia Giedrimiene; Christine Niekrash; Alvydas Gleiznys; Jurgina Sakalauskiene; Astra Vitkauskiene

doi:10.12659/MSM.932243

26 October 2021 : Clinical Research

Expression of Interleukin-17, Tumor Necrosis Factor-Alpha, and Matrix Metalloproteinase-8 in Patients with Chronic Peri-Implant Mucositis

Darius Gleiznys^1ABCDEFG*, Albertas Kriauciunas^1BCDE, Julius Maminskas^1AB, Arturas Stumbras^2FG, Dalia Giedrimiene^3CD, Christine Niekrash^4CDE, Alvydas Gleiznys^5AD, Jurgina Sakalauskiene^1ABEF, Astra Vitkauskiene^6ACDE

DOI: 10.12659/MSM.932243

Med Sci Monit 2021; 27:e932243

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Table 3 The levels of MMP-8, IL-17, and TNF-α in peri-implant crevicular fluid of healthy subjects and the mucositis patients untreated and treated groups.

Study groups	MMP-8	IL-17	TNF-α
Study groups	Median [25–75%]
HP, n=30	0.99 [0.68–1.4]	1.87 [0.83–3.24]	0.7 [0.53–0.74]
MP, n=30	3.27 [2.46–7.24]	17.94 [14.44–20.56]	3.08 [2.69–3.82]
TP, n=30	1.70 [0.53–3.05]	6.35 [4.43–6.75]	1.52 [1.17–1.88]
	χ=39.671, df=2, <0.001	χ=77.615, df=2, <0.001	χ=79.137, df=2, <0.001
	<0.001
χ – by Kruskal-Wallis test, multiple comparisons by Mann-Whitney test; df – degrees of freedom. HP – healthy subjects; MP – patients with untreated peri-implant mucositis; TP – patients treated with mechanical anti-infective therapies for mucositis.

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Expression of Interleukin-17, Tumor Necrosis Factor-Alpha, and Matrix Metalloproteinase-8 in Patients with Chronic Peri-Implant Mucositis

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