01 December 2021: Clinical Research
A Retrospective Observational Study of the Association Between Plasma Levels of Interleukin 8 in 42 Patients with Sepsis-Induced Myocardial Dysfunction at a Single Center Between 2017 and 2020
XiaoYing Chen 1ABC , Xian Liu 1BE , RuiAn Dong 1BE , Dan Zhang 1AG** , Shu Qin 2AG**DOI: 10.12659/MSM.933065
Med Sci Monit 2021; 27:e933065
Table 2 Comparison of immune parameters and inflammatory mediators between the 2 groups.
| Variables | Total (n=256) | SIMD (n=42) | NO-SIMD (n=214) | P |
|---|---|---|---|---|
| C3, g/L | 0.65 (0.54, 0.85) | 0.63 (0.54, 0.70) | 0.65 (0.54, 0.86) | 0.148 |
| C4, g/L | 0.20±0.62 | 0.18±0.04 | 0.21±0.07 | 0.028 |
| CD4, /ul | 216.00 (134.00, 344.00) | 175.50 (84.50, 259.75) | 239.00 (137.00, 366.00) | 0.055 |
| CD8, /ul | 162.00 (103.00, 365.00) | 148.00 (85.25, 250.50) | 173.00 (112.25, 377.00) | 0.064 |
| CD4/8 | 1.34 (0.72, 1.97) | 1.29 (0.59, 2.01) | 1.36 (0.73, 1.91) | 0.795 |
| IL-1β, pg/mL | 5.00 (4.90, 5.0) | 5.00 (5.00, 5.86) | 4.90 (4.90, 5.00) | |
| IL-2R, IU/mL | 1231.00 (591.25, 2760.00) | 1673.00 (1027.00, 4024.25) | 1136.50 (584.00, 2744.00) | 0.015 |
| IL-6, pg/mL | 61.15 (27.00, 335.00) | 107.50 (34.10, 394.43) | 57.20 (26.88, 334.00) | 0.123 |
| IL-8, pg/mL | 64.45 (17.60, 162.22) | 133.90 (80.20, 402.79) | 46.35 (16.80, 125.00) | |
| IL-10, pg/mL | 8.575 (4.90, 29.03) | 19.40 (8.78, 55.86) | 7.10 (4.90, 26.05) | 0.002 |
| SIMD – sepsis-induced myocardial dysfunction; C – complement; CD – cluster of differentiation; IL – interleukin; – test was used for comparison between SIMD group and NO-SIMD group; – Mann-Whitney U test was used for comparison between SIMD group and NO-SIMD group. | ||||