23 December 2021 : Clinical Research
Postoperative Complications Associated with Moderate Sedation in Endoscopic Procedures Among Patients with Cirrhosis
Yan Wang1B, Huisheng Xu12C, Hui Li1E, Lingyang Chen3B, Ye Xin4C, Hongtan Chen5D, Xiangming Fang1E*, Baoli Cheng1ADOI: 10.12659/MSM.933082
Med Sci Monit 2021; 27:e933082
Table 4 Predictors of moderate sedation-associated postoperative complications: unadjusted bivariate analysis.
| Independent variable | Patients, n | Cardiac, n (%) | Patient Injury, n (%) | Procedure, n (%) | Serious, n (%) | Any, n (%) |
|---|---|---|---|---|---|---|
| Age, y | ||||||
| 18–49 | 62 | 0 (0) | 0 (0) | 9 (14.5) | 0 (0) | 9 (14.5) |
| ≥50 | 170 | 7 (4.1) | 1 (0.6) | 26 (15.3) | 8 (4.7) | 31 (18.2) |
| value | 0.235 | 1.000 | 0.884 | 0.183 | 0.507 | |
| Sex | ||||||
| Female | 70 | 2 (2.9) | 1 (1.4) | 8 (11.4) | 3 (4.3) | 11 (15.7) |
| Male | 162 | 5 (3.1) | 0 (0) | 27 (16.7) | 5 (3.1) | 29 (11.7) |
| value | 1.000 | 0.302 | 0.306 | 0.946 | 0.686 | |
| ASA | ||||||
| 1/2 | 42 | 2 (4.8) | 0 (0) | 5 (11.9) | 2 (4.8) | 6 (14.3) |
| ≥3 | 190 | 5 (2.6) | 1 (0.5) | 30 (15.8) | 6 (3.2) | 34 (17.9) |
| value | 0.817 | 1.000 | 0.524 | 0.961 | 0.575 | |
| Child-Pugh | ||||||
| A | 199 | 5 (2.5) | 1 (0.5) | 31 (15.6) | 6 (3.0) | 35 (17.6) |
| B+C | 33 | 2 (6.1) | 0 (0) | 4 (12.1) | 2 (6.1) | 5 (15.2) |
| value | 0.270 | 0.683 | 0.607 | 0.375 | 0.731 | |
| Procedure | ||||||
| EGD | 221 | 7 (3.2) | 1 (0.5) | 34 (15.4) | 8 (3.6) | 39 (17.6) |
| Enteroscopy | 11 | 0 (0) | 0 (0) | 1 (9.1) | 0 (0) | 1 (9.1) |
| value | 0.549 | 0.823 | 0.159 | 0.521 | 0.463 | |
| Portal hypertension history | ||||||
| Yes | 158 | 7 (4.4) | 1 (0.6) | 27 (17.1) | 8 (5.1) | 32 (20.3) |
| No | 74 | 1 (1.4) | 0 (0) | 8 (10.8) | 1 (1.4) | 8 (10.8) |
| value | 0.417 | 1.000 | 0.213 | 0.317 | 0.076 | |
| Cardiac comorbidities | ||||||
| Yes | 42 | 1 (2.4) | 0 (0) | 4 (9.5) | 1 (2.4) | 4 (9.5) |
| No | 190 | 7 (3.7) | 1 (0.5) | 31 (16.3) | 8 (4.2) | 36 (18.9) |
| value | 1.000 | 1.000 | 0.266 | 0.909 | 0.143 | |
| Diabetes mellitus | ||||||
| Yes | 24 | 1 (4.2) | 0 (0) | 5 (20.8) | 1 (4.2) | 5 (20.8) |
| No | 208 | 7 (3.4) | 1 (0.5) | 30 (14.4) | 8 (3.8) | 35 (16.8) |
| value | 1.000 | 1.000 | 0.596 | 1.000 | 0.836 | |
| Shift | ||||||
| Daytime | 161 | 3 (1.9) | 1 (0.6) | 21 (13.0) | 3 (1.9) | 17 (10.6) |
| Evening | 71 | 4 (5.6) | 0 (0) | 14 (19.7) | 5 (7.0) | 23 (32.4) |
| value | 0.205 | 1.000 | 0.191 | 0.109 | <0.001 | |
| ASA – American Society of Anesthesiologists; EGD – esophagogastroduodenoscopy. | ||||||