24 January 2022>: Clinical Research
Correlation Between Severity of Illness and Levels of Free Triiodothyronine, Interleukin-6, and Interleukin-10 in Patients with Acute Pancreatitis
Fei Tian ABCDEFG , Tianjiao Lin ABCDEF , Qingyun Zhu ABC , Youdong Wan ABC , Ziqian Wu C , Shaoyan Lv C , Jingyu Song C , Ruomeng Li BE , Yunyun Wang E , Yushi Zhang D , Xu Yan E , Xinting Pan ABCDEFG*DOI: 10.12659/MSM.933230
Med Sci Monit 2022; 28:e933230
Table 1 Comparison of general data of patients with between the SAP group and non-SAP group.
Variable | SAP group (n=92) | Non-SAP group (n=220) | P value |
---|---|---|---|
Age, years | 56.82±14.79 | 56.19±17.69 | 0.745 |
Sex, Male/Female | 61/31 | 142/78 | 0.766 |
Etiology | * | ||
BAP | 56 | 60 | |
HTGAP | 28 | 70 | |
BAP+HTGAP | 8 | 10 | |
AAP | 0 | 2 | |
Others | 0 | 78 | |
BMI, kg/m | 25.53±6.26 | 24.09±3.03 | 0.649 |
Alcohol, yes/no | 48/44 | 74/146 | 0.002 |
Tobacco, yes/no | 40/52 | 78/142 | 0.183 |
TSH, ng/ml | 0.81±1.40 | 0.89±1.26 | 0.651 |
FT4, nmol/L | 12.58±3.49 | 14.76±2.38 | * |
FT3, nmol/L | 2.53±1.03 | 3.45±0.86 | * |
LDH, U/L | 1.84±1.19 | 1.29±0.66 | 0.002 |
PLT(48), 10/L | 240.79±106.09 | 274.26±79.64 | 0.007 |
Tbil, μmol/L | 37.82±29.44 | 24.29±28.25 | * |
* | |||
Cr, μmol/L | 118.32±140.51 | 102.04±102.94 | 0.256 |
* | |||
* | |||
* | |||
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IL-10, pg/ml | 5.64±13.6 | 1.4±1.37 | * |
IL-1β, pg/ml | 20.76±42.7 | 2.29±1.7 | * |
IL-2, pg/ml | 99.05±634.66 | 1.95±2.92 | 0.024 |
IL-4, pg/ml | 2.48±4.86 | 1.17±2.79 | 0.003 |
IL-5, pg/ml | 2.16±2.41 | 0.85±0.45 | * |
IL-6, pg/ml | 106.63±165.52 | 23.01±150.78 | * |
IL-8, pg/ml | 262.22±1372.12 | 5.02±12.16 | 0.006 |
* | |||
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Ranson score | 3.88±2.30 | 2.54±2.31 | * |
APACHE II score | 18.36±8.37 | 6.49±4.51 | * |
Data are presented as the mean±SD * value BAP – biliary acute pancreatitis; HTGAP – hypertriglycemic acute pancreatitis; AAP – alcohol-induced acute pancreatitis; BMI – body mass index; LDH – lactate; PLT – platelet; Tbil – total bilirubin; Cr – creatinine; TSH – thyroid-stimulating hormone; FT4 – free tetraiodothyronine; FT3 – free triiodothyronine. |