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24 January 2022: Clinical Research

Correlation Between Severity of Illness and Levels of Free Triiodothyronine, Interleukin-6, and Interleukin-10 in Patients with Acute Pancreatitis

Fei Tian ABCDEFG , Tianjiao Lin ABCDEF , Qingyun Zhu ABC , Youdong Wan ABC , Ziqian Wu C , Shaoyan Lv C , Jingyu Song C , Ruomeng Li BE , Yunyun Wang E , Yushi Zhang D , Xu Yan E , Xinting Pan ABCDEFG*

DOI: 10.12659/MSM.933230

Med Sci Monit 2022; 28:e933230

Table 1 Comparison of general data of patients with between the SAP group and non-SAP group.

VariableSAP group (n=92)Non-SAP group (n=220)P value
Age, years56.82±14.7956.19±17.690.745
Sex, Male/Female61/31142/780.766
Etiology*
 BAP5660
 HTGAP2870
 BAP+HTGAP810
 AAP02
 Others078
BMI, kg/m25.53±6.2624.09±3.030.649
Alcohol, yes/no48/4474/1460.002
Tobacco, yes/no40/5278/1420.183
TSH, ng/ml0.81±1.400.89±1.260.651
FT4, nmol/L12.58±3.4914.76±2.38*
FT3, nmol/L2.53±1.033.45±0.86*
LDH, U/L1.84±1.191.29±0.660.002
PLT(48), 10/L240.79±106.09274.26±79.640.007
Tbil, μmol/L37.82±29.4424.29±28.25*
*
Cr, μmol/L118.32±140.51102.04±102.940.256
*
*
*
*
*
*
IL-10, pg/ml5.64±13.61.4±1.37*
IL-1β, pg/ml20.76±42.72.29±1.7*
IL-2, pg/ml99.05±634.661.95±2.920.024
IL-4, pg/ml2.48±4.861.17±2.790.003
IL-5, pg/ml2.16±2.410.85±0.45*
IL-6, pg/ml106.63±165.5223.01±150.78*
IL-8, pg/ml262.22±1372.125.02±12.160.006
*
*
*
*
Ranson score3.88±2.302.54±2.31*
APACHE II score18.36±8.376.49±4.51*
Data are presented as the mean±SD
* value
BAP – biliary acute pancreatitis; HTGAP – hypertriglycemic acute pancreatitis; AAP – alcohol-induced acute pancreatitis; BMI – body mass index; LDH – lactate; PLT – platelet; Tbil – total bilirubin; Cr – creatinine; TSH – thyroid-stimulating hormone; FT4 – free tetraiodothyronine; FT3 – free triiodothyronine.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750