Salicylate Induced GABAAR Internalization by Dopamine D1-Like Receptors Involving Protein Kinase C (PKC) in Spiral Ganglion Neurons

Jiangyuan Qin; Tingjia Wei; Huiying Chen; Xiaoyu Lin; Danxue Qin; Fangyu Wei; Peiqiang Liu; Wenhua Ye; Jiping Su

doi:10.12659/MSM.933278

18 October 2021 : Laboratory Research

Salicylate Induced GABAAR Internalization by Dopamine D1-Like Receptors Involving Protein Kinase C (PKC) in Spiral Ganglion Neurons

Jiangyuan Qin^1ABCDEF, Tingjia Wei^1BCD, Huiying Chen^1BCD, Xiaoyu Lin^1BC, Danxue Qin^1BC, Fangyu Wei^1BC, Peiqiang Liu^1BC, Wenhua Ye^1BC, Jiping Su^1ADG*

DOI: 10.12659/MSM.933278

Med Sci Monit 2021; 27:e933278

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Supplementary Table 3 Data of Figure 4, GABARγ2 p-S327 protein expression in the absence or presence of Bis I.

Groups	Density (mean±SD)		Relative expression as% of control (mean±SD)
Groups	GABARγ2 p-S327	Total βIII-tubulin	GABARγ2 p-S327
Ctrl	122.49±29.52	203.93±23.46	100±0.00
SKF	209.16±20.65	199.78±14.07	174.49±19.42
SKF+SCH	128.83±18.51	192.37±11.39	111.57±10.49
Bis I	102.42±29.59	192.76±9.11	88.58±15.32
SKF+Bis I	169.62±11.63	198.74±5.85	142.12±5.49
SKF+SCH+Bis I	145.26±20.81	201.31±19.52	120.14±16.92
Ctrl	83.82±19.37	186.92±14.93	100±0.00
SS	160.27±23.26	191.88±3.13	185.48±27.05
SS+SKF	162.13±26.45	186.42±12.18	193.28±30.23
SS+SKF+SCH	115.98±23.08	181.09±10.15	141.82±41.26
SS+Bis I	113.96±22.41	186.47±1.82	135.70±31.09
SS+SKF+Bis I	109.24±18.63	182.13±24.46	134.02±32.55
SS+SKF+SCH+Bis I	112.55±14.60	178.71±16.77	139.59±51.96

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Salicylate Induced GABAAR Internalization by Dopamine D1-Like Receptors Involving Protein Kinase C (PKC) in Spiral Ganglion Neurons

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