12 April 2022 : Clinical Research
Development and Validation of a Nomogram for Predicting Postoperative Distant Metastasis in Patients with Cervical Cancer
Weihong Zeng1ABCDE, Lishan Huang1BCD, Haihong Lin1BCD, Ru Pan1BCD, Haochang Liu1BCD, Jizhong Wen1BCD, Ye Liang1BCD, Haikun Yang1AE*DOI: 10.12659/MSM.933379
Med Sci Monit 2022; 28:e933379
Table 5 Results of subgroup analysis in the external validation set.
| Variables | External validation set (n=561) | AUC (95% CI) |
|---|---|---|
| Age | ||
| <60 | 463 | 0.655 (0.570–0.740) |
| ≥60 | 98 | 0.504 (0.314–0.695) |
| Histologic type | ||
| Squamous cell carcinoma | 467 | 0.636 (0.553–0.718) |
| Adenocarcinoma | 72 | 0.811 (0.618–1.000) |
| Adenosquamous carcinoma | 9 | NA |
| Others | 13 | 0.636 (0.369–0.904) |
| T stage | ||
| T1 | 361 | 0.598 (0.472–0.724) |
| T2 | 195 | 0.473 (0.352–0.594) |
| Treatment | ||
| Surgery | 245 | 0.670 (0.515–0.824) |
| Surgery+chemotherapy | 11 | 0.639 (0.272–1.000) |
| Surgery+radiotherapy | 183 | 0.537 (0.391–0.683) |
| Surgery+radiotherapy+chemotherapy | 122 | 0.585 (0.450–0.720) |
| Tumor size | ||
| <4 | 473 | 0.650 (0.562–0.737) |
| ≥4 | 88 | 0.548 (0.285–0.812) |
| Regional nodes positive | ||
| No | 22 | NA |
| Yes | 538 | 0.630 (0.550–0.710) |
| AUC – area under the curve; CI – confidence interval; NA – not available. | ||