14 November 2021 : Clinical Research
Clinical Features and Temporal Lung Radiographic Changes in 25 Patients Recovering from COVID-19 Pneumonia: A Retrospective Case-Control Study
Chao Hu1ABCDEG, Jian Ping Zeng2ACDFG, Ke Peng3ABCDF, Hong Xia4BCEF, Huan Ming Zhang5BCDEF, Zhi Zhong5BCDE, Ming Yan Jiang1ABDFG*DOI: 10.12659/MSM.933381
Med Sci Monit 2021; 27:e933381
Table 1 Comparison of demographic and clinical characteristics between patients with moderate and severe COVID-19 pneumonia.
| Moderate (n=17) | Severe (n=9) | P | |
|---|---|---|---|
| Age, years | 43.76±12.89 | 52.44±11.88 | 0.087 |
| Sex | 0.42 | ||
| Male | 8 (47.06%) | 6 (66.67%) | |
| Female | 10 (58.82%) | 3 (33.33%) | |
| BMI | 23.66±3.72 | 25.95±3.38 | 0.545 |
| Current smoking | 1 (5.88%) | 2 (22.22%) | 0.25 |
| Comorbidity | 6 (35.29%) | 4 (44.44%) | 0.81 |
| HBP | 2 (11.77%) | 2 (22.22%) | 0.444 |
| DM | 2 (11.77%) | 2 (22.22%) | 0.444 |
| History of surgery | 4 (23.53%) | 2 (22.22%) | 1 |
| COPD | 0 (0.00%) | 1 (11.11%) | 0.15 |
| Cerebrovascular disease | 1 (5.88%) | 0 (0.00%) | 0.471 |
| Chronic liver | 2 (11.77%) | 0 (0.00%) | 0.299 |
| CKD | 0 (0.00%) | 1 (11.11%) | 0.15 |
| Other | 1 (5.88%) | 1 (11.11%) | 0.603 |
| Fever | 9 (52.94%) | 5 (55.56%) | 0.785 |
| Dyspnea | 1 (5.88%) | 2 (22.22%) | 0.25 |
| Myalgia or fatigue | 8 (47.06%) | 4 (44.44%) | 1 |
| Cough or sputum | 13 (76.47%) | 7 (77.78%) | 0.756 |
| Diarrhea | 2 (11.77%) | 0 (0%) | – |
| Virus nucleic acid negative* | 12 (70.59%) | 1 (11.11%) | 0.015 |
| Time of aggravation | 10.22±3.73 | ||
| * SARS-CoV-2 virus nucleic acid turned negative within 10 days after admission. BMI – body mass index; HBP – high blood pressure; DM – diabetes mellitus; COPD – chronic obstructive pulmonary disease; CKD – chronic kidney disease. | |||