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10 November 2021 : Clinical Research  

Evaluation of Susceptibility Genes/Loci Associated with Male Androgenetic Alopecia (MAGA) for Female-Pattern Hair Loss in a Chinese Han Population and a Brief Literature Review

Bo Liang123AG, Yantao Ding123B, Yi Zhou123D, Chunjun Yang4BF*, Zhixiang Cheng5FG

DOI: 10.12659/MSM.933424

Med Sci Monit 2021; 27:e933424

Table 1 Case-control association analysis for SNPs associated with MAGA in FPHL samples.

CHRLocusSNPBPAlleleRefOR (95% CI)P*FDRCall-ratePower (%)
11p36.22rs1256572711033082G/A[]11 0.83 (0.58–1.19)0.3070.8440.99151
22q35rs10193725219726498C/T[]12 0.95 (0.67–1.35)0.7781.0000.97639
22q35rs7349332219756383T/C0.97 (0.65–1.42)0.8580.9930.98647
22q37.3rs9752491239734678A/G[]11 0.59 (0.35–0.98)0.0410.9020.98329
22q37.3rs9711321239697444C/T1.40 (0.91–2.17)0.1260.9240.97129
22q37.3rs12613833239749411C/T0.88 (0.62–1.25)0.4850.6670.97648
33q25.1rs4679955151653368T/A[]12 1.16 (0.82–1.62)0.4060.6870.98126
55q33.3rs929626158310631A/G0.95 (0.66–1.36)0.7870.9620.98125
55q33.3rs1081073158381512T/A1.02 (0.72–1.44)0.9290.9730.98323
77p21.1rs224981718862536A/G[]10 0.76 (0.53–1.09)0.1280.7040.98689
77p21.1rs1205628218848728C/T0.78 (0.47–1.30)0.3450.7590.98199
77p21.1rs75685318856525A/G0.85 (0.61–1.19)0.3560.6530.98595
77p21.1rs1323014218848034A/G0.82 (0.48–1.39)0.4540.6660.983100
77p21.1rs1735035518895028A/G1.00 (0.71–1.42)0.980.9800.98321
1212p12.1rs797501726428793T/C[]12 1.22 (0.81–1.85)0.3460.6920.98123
1212p12.1rs966881026426420C/T0.87 (0.62–1.22)0.4260.6690.98832
1818q12.3rs1050286142800148T/C[]11 0.97 (0.61–1.55)0.8960.9860.97830
2020p11rs613744421733639C/T[]14 0.71 (0.49–1.02)0.060.6600.98698
2020p11rs218043921801100C/T0.76 (0.54–1.09)0.1330.5850.98899
2020p11rs199807621828045A/G0.77 (0.54–1.10)0.1470.5390.986100
2020p11rs611349122005415A/C1.26 (0.89–1.77)0.1910.6000.9997
2020p11rs20157121961514T/C1.18 (0.84–1.67)0.3340.8160.98698
BP – NCBI build 37; CI – confidence interval; OR – odds ratio.
* P-values were calculated using the Armitage trend.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750