Evaluation of Susceptibility Genes/Loci Associated with Male Androgenetic Alopecia (MAGA) for Female-Pattern Hair Loss in a Chinese Han Population and a Brief Literature Review

Bo Liang; Yantao Ding; Yi Zhou; Chunjun Yang; Zhixiang Cheng

doi:10.12659/MSM.933424

10 November 2021 : Clinical Research

Evaluation of Susceptibility Genes/Loci Associated with Male Androgenetic Alopecia (MAGA) for Female-Pattern Hair Loss in a Chinese Han Population and a Brief Literature Review

Bo Liang^123AG, Yantao Ding^123B, Yi Zhou^123D, Chunjun Yang^4BF*, Zhixiang Cheng^5FG

DOI: 10.12659/MSM.933424

Med Sci Monit 2021; 27:e933424

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Table 2 Candidate variant analyses of MAGA susceptibility locus studies for FPHL.

Gene/locus	Population	Case-control association study		Results	Ref
Gene/locus	Population	Cases	Controls	Results	Ref
AR/EDA2R	UK	145	179	Subgroup analysis of UK patients revealed significant associations for seven variants in patients with an early age of onset	Redler et al., Br J Dermatol. 2012 []²⁰
	Germany	85	150		Redler et al., Br J Dermatol. 2012 []²⁰
	Han Chinese	200	200	Negative	Rui et al., Dermatology. 2016 []²¹
1p36	UK	145	469	Negative	Redler et al., J Dermatol Sci. 2013 []²²
1p36	Germany	260	469	Negative	Redler et al., J Dermatol Sci. 2013 []²²
2q35	UK	145	179	Negative	Nuwayhid et al., Arch Dermatol Res. 2014 []²³
2q35	Germany	440	500	Negative	Nuwayhid et al., Arch Dermatol Res. 2014 []²³
2q37	UK	145	469	Negative	Redler et al., J Dermatol Sci. 2013 []²²
2q37	Germany	260	469	Negative	Redler et al., J Dermatol Sci. 2013 []²²
3q25.1	UK	145	179	Negative	Nuwayhid et al., Arch Dermatol Res. 2014 []²³
3q25.1	Germany	440	500	Negative
5q33.3	UK	145	469	Negative
5q33.3	Germany	260	469	Negative
7p21.1	UK	145	469	Negative	Redler et al., J Dermatol Sci. 2013 [²²
7p21.1	Germany	260	469	Negative
7q11.22	UK	145	469	Negative
7q11.22	Germany	260	469	Negative
12p12.1	UK	145	179	Negative	Nuwayhid et al., Arch Dermatol Res. 2014 []²³
12p12.1	Germany	440	500	Negative	Nuwayhid et al., Arch Dermatol Res. 2014 []²³
17q21.31	UK	145	469	Negative	Redler et al., J Dermatol Sci. 2013 []²²
17q21.31	Germany	260	469	Negative
18q21.1	UK	145	469	Negative
18q21.1	Germany	260	469	Negative
20p11	UK	145	179	Negative	Redler et al., Br J Dermatol. 2012 []²⁰
20p11	Germany	85	150	Negative	Redler et al., Br J Dermatol. 2012 []²⁰

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Evaluation of Susceptibility Genes/Loci Associated with Male Androgenetic Alopecia (MAGA) for Female-Pattern Hair Loss in a Chinese Han Population and a Brief Literature Review

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