H2A Histone Family Member Z (H2AFZ) Serves as a Prognostic Biomarker in Lung Adenocarcinoma: Bioinformatic Analysis and Experimental Validation

14 January 2022: Database Analysis

Zongkuo Li ^12AE , Menglong Hu ^12A , Jinhuan Qiu ^12C , Junkai Feng ^12C , Ruizhen Zhang ^1C , Huifang Wu ^1D , Guiming Hu ^1D , Jingli Ren ^1G*

DOI: 10.12659/MSM.933447

Med Sci Monit 2022; 28:e933447

Table 1 Association between H2AFZ expression and clinicopathologic characteristics in patients with LUAD in TCGA-LUAD cohort.

Characteristics	H2AFZ expression		Total	p Value
Characteristics	Low (n=220)	High (n=219)	Total	p Value
Age
	93	103	196	0.316
≥65	127	116	243	0.316
Gender
Male	88	113	201
Female	132	106	238
Pathological stage
I	139	100	239
II	44	61	105
III	31	43	74
IV	6	15	21
T classification
T1	92	61	153
T2	102	128	230
T3	17	21	38
T4	9	9	18
N classification
N0	160	130	290
N1	33	49	82
N2	26	39	65
N3	1	1	2
Bold values indicate