14 January 2022 : Database Analysis
H2A Histone Family Member Z (H2AFZ) Serves as a Prognostic Biomarker in Lung Adenocarcinoma: Bioinformatic Analysis and Experimental Validation
Zongkuo Li12AE, Menglong Hu12A, Jinhuan Qiu12C, Junkai Feng12C, Ruizhen Zhang1C, Huifang Wu1D, Guiming Hu1D, Jingli Ren1G*DOI: 10.12659/MSM.933447
Med Sci Monit 2022; 28:e933447
Table 4 Univariate analysis and multivariate analysis of the correlation of H2AFZ expression with OS among LUAD patients in TCGA cohort.
| Parameters | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p Value | HR | 95% CI | p Value | |
| Age | 1.012 | 0.995–1.029 | 0.145 | 1.020 | 1.004–1.037 | 0.017 |
| Gender | 1.084 | 0.787–1.493 | 0.619 | 0.900 | 0.649–1.248 | 0.526 |
| Pathological stage | 1.655 | 1.426–1.921 | 1.500 | 1.204–1.868 | ||
| T classification | 1.535 | 1.259–1.872 | 1.176 | 0.950–1.455 | 0.136 | |
| N classification | 1.699 | 1.419–2.033 | 1.162 | 0.907–1.488 | 0.236 | |
| H2AFZ | 1.499 | 1.189–1.891 | 1.494 | 1.185–1.884 | ||
| Bold values indicate | ||||||