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14 January 2022: Database Analysis

H2A Histone Family Member Z (H2AFZ) Serves as a Prognostic Biomarker in Lung Adenocarcinoma: Bioinformatic Analysis and Experimental Validation

Zongkuo Li 12AE , Menglong Hu 12A , Jinhuan Qiu 12C , Junkai Feng 12C , Ruizhen Zhang 1C , Huifang Wu 1D , Guiming Hu 1D , Jingli Ren 1G*

DOI: 10.12659/MSM.933447

Med Sci Monit 2022; 28:e933447

Table 6 Gene sets enriched in the high H2AFZ expression phenotype.

Gene set nameNESNOM p-valueFDR q-value
HALLMARK_MTORC1_SIGNALING2.660.0000.000
HALLMARK_MYC_TARGETS_V12.500.0000.000
HALLMARK_DNA_REPAIR2.400.0000.000
HALLMARK_G2M_CHECKPOINT2.390.0000.000
HALLMARK_E2F_TARGETS2.370.0000.000
HALLMARK_UNFOLDED_PROTEIN_RESPONSE2.290.0000.000
HALLMARK_MYC_TARGETS_V22.240.0000.000
HALLMARK_OXIDATIVE_PHOSPHORYLATION2.180.0000.001
HALLMARK_PI3K_AKT_MTOR_SIGNALING2.160.0000.001
HALLMARK_MITOTIC_SPINDLE1.880.0120.015
NES – normalized enrichment score; NOM – nominal; FDR – false discovery rate.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750