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16 January 2022: Database Analysis

Junctional Adhesion Molecule-Like Protein (JAML) Is Correlated with Prognosis and Immune Infiltrates in Lung Adenocarcinoma

Likui Fang ABCDEF , Wenfeng Yu BCD , Guocan Yu CDF , Fangming Zhong DF , Bo Ye ABCDEF*

DOI: 10.12659/MSM.933503

Med Sci Monit 2022; 28:e933503

Table 2 Cox regression analysis of JAML and clinicopathologic characteristics with survival outcomes in LUAD.

CharacteristicsUnivariate analysisMultivariate analysis
Overall survival
 Age (>65 vs ≤65)1.2230.916–1.6350.172
 Gender (Male vs Female)1.0700.803–1.4260.642
 Smoking history (Yes vs No)0.8940.592–1.3480.591
 T stage (T2 & T3 & T4 vs T1)1.7281.229–2.4310.0021.6421.050–2.5680.030
 N stage (N1 & N2 & N3 vs N0)2.6011.944–3.4801.8371.029–3.2800.040
 M stage (M1 vs M0)2.1361.248–3.6530.0061.4130.765–2.6100.270
 Pathologic stage (Stage II & Stage III & Stage IV vs Stage I)2.9332.173–3.9581.4350.769–2.6770.257
 JAML (High vs Low)0.6180.460–0.8310.0010.7060.500–0.9970.048
Progress free survival
 Age (>65 vs ≤65)1.0230.784–1.3350.867
 Gender (Male vs Female)1.1720.901–1.5260.236
 Smoking history (Yes vs No)0.9680.658–1.4260.870
 T stage (T2 & T3 & T4 vs T1)1.8821.379–2.5701.5091.090–2.0900.013
 N stage (N1 & N2 & N3 vs N0)1.5121.152–1.9840.0030.8510.562–1.2880.445
 M stage (M1 vs M0)1.5130.855–2.6760.155
 Pathologic stage (Stage II & Stage III & Stage IV vs Stage I)1.9601.502–2.5571.8511.221–2.8060.004
 JAML (High vs Low)0.7580.581–0.9890.0410.8460.644–1.1110.229

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750