01 February 2022 : Database Analysis
A Novel Predictive Model Incorporating Ferroptosis-Related Gene Signatures for Overall Survival in Patients with Lung Adenocarcinoma
Yuli Wang
1ABE, Yanbin Pan1BC, Jianchun Wu1AD, Yingbin Luo1B, Zhihong Fang1F, Rongzhong Xu1F, Wenjing Teng1DF, Min Chen1AF, Yan Li1AG*
DOI: 10.12659/MSM.934050
Med Sci Monit 2022; 28:e934050
Table 1 Clinical characteristics of the LUAD patients enrolled in the present study.
| Characteristics | TCGA-LUAD | GEO-LUAD |
|---|---|---|
| 522 | 443 | |
| 65.33 (33–88) | 64.42 (33–87) | |
| Female | 280 (53.6%) | 220 (49.7%) |
| Male | 242 (46.4%) | 223 (50.3%) |
| Stage (%) | ||
| I | 279 (53.4%) | 276 (62.3%) |
| II | 124 (23.8%) | 95 (21.4%) |
| III | 85 (16.3%) | 69 (15.6%) |
| IV | 26 (5.0%) | 0 |
| Unknown | 8 (1.5%) | 3 (0.7%) |
| T1 | 172 (33.0%) | 150 (33.9%) |
| T2 | 281 (53.8%) | 251 (56.7%) |
| T3 | 47 (9.0%) | 28 (6.3%) |
| T4 | 19 (3.6%) | 12 (2.7%) |
| Tx | 3 (0.6%) | 2 (0.4%) |
| N0 | 335 (64.1%) | 299 (67.5%) |
| N1 | 98 (18.8%) | 88 (19.8%) |
| N2 | 75 (14.4%) | 53 (12.0%) |
| N3 | 2 (0.4) | 0 |
| Nx | 11 (2.1%) | 3 (0.7%) |
| Unknown | 1 (0.2) | 0 |
| M0 | 353 (67.6%) | NA |
| M1 | 25 (4.8%) | NA |
| Mx | 140 (26.8%) | NA |
| Unknown | 4 (0.8%) | NA |
| OS days (median) | 902.5 | 1578 |