01 February 2022 : Database Analysis
A Novel Predictive Model Incorporating Ferroptosis-Related Gene Signatures for Overall Survival in Patients with Lung Adenocarcinoma
Yuli Wang
1ABE, Yanbin Pan1BC, Jianchun Wu1AD, Yingbin Luo1B, Zhihong Fang1F, Rongzhong Xu1F, Wenjing Teng1DF, Min Chen1AF, Yan Li1AG*
DOI: 10.12659/MSM.934050
Med Sci Monit 2022; 28:e934050
Table 2 Baseline clinical features of the LUAD patients in both groups.
| Characteristics | TCGA-LUAD cohort | GEO-LUAD | ||||
|---|---|---|---|---|---|---|
| High risk | Low risk | p-value | High risk | Low risk | p-value | |
| Female | 123 (49.2%) | 147 (58.8%) | 0.031 | 7 (41.2%) | 212 (49.9%) | 0.481 |
| Male | 127 (50.8%) | 103 (41.2%) | 10 (58.8%) | 213 (50.1%) | ||
| ≤65 | 129 (51.6%) | 108 (43.2%) | 0.068 | 9 (52.9%) | 222 (52.2%) | 0.954 |
| >66 | 116 (46.4%) | 137 (54.8%) | 8 (47.1%) | 203 (47.8%) | ||
| Unknown | 5 (2.0%) | 5 (2.0%) | 0 | 0 | ||
| I+II | 178 (71.2%) | 209 (83.6%) | 0.001 | 11 (64.7%) | 360 (84.7%) | 0.030 |
| III+IV | 68 (27.2%) | 37 (14.8%) | 6 (35.3%) | 62 (14.6%) | ||
| Unknown | 4 (1.6%) | 4 (1.6%) | 0 | 3 (0.7%) | ||