11 January 2022 : Clinical Research
Association Between Hyperhomocysteinemia Combined with Metabolic Syndrome and Higher Prevalence of Stroke in Chinese Adults Who Have Elevated Blood Pressure
Feng Hu12BCDEF, Shichao Yu3BCD, Juan Li4ABCD, Wei Zhou25BDEF, Tao Wang25BCDE, Xiao Huang125AF*, Huihui Bao125AG, Xiaoshu Cheng125AGDOI: 10.12659/MSM.934100
Med Sci Monit 2022; 28:e934100
Table 3 Effect size of combined HHcy and MS on the prevalence of stroke in different models compared to its isolated forms.
| Variables | Crude Model | Model I | Model II | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Isolated HHcy | Ref | Ref | Ref | |||
| HHcy+MS | 1.36 (1.15, 1.61) | 1.57 (1.32, 1.87) | 1.78 (1.47, 2.15) | |||
| Isolated MS | Ref | Ref | Ref | |||
| HHcy+MS | 1.68 (1.39, 2.03) | 1.47 (1.21, 1.78) | 1.39 (1.13, 1.70) | 0.002 | ||
| HHcy – hyperhomocysteinemia; MS – metabolic syndrome; Ref – reference; OR – odds ratio; CI – confidence interval. Model I adjusted for age and sex. Model II adjusted for sex, BMI, smoking and drinking status, eGFR and serum uric acid. | ||||||