Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

11 January 2022: Clinical Research

Association Between Hyperhomocysteinemia Combined with Metabolic Syndrome and Higher Prevalence of Stroke in Chinese Adults Who Have Elevated Blood Pressure

Feng Hu 12BCDEF , Shichao Yu 3BCD , Juan Li 4ABCD , Wei Zhou 25BDEF , Tao Wang 25BCDE , Xiao Huang 125AF , Huihui Bao 125AG* , Xiaoshu Cheng 125AG*

DOI: 10.12659/MSM.934100

Med Sci Monit 2022; 28:e934100

Supplementary Table 1 Associations of covariates with stroke occurrence.

CovariatesOR (95% CI)P value
Age (years)1.01 (1.01, 1.02)
 Female0.63 (0.55, 0.72)
BMI (kg/m)0.99 (0.97, 1.00)0.124
Heart rate (times/min)1.00 (0.99, 1.00)0.227
Smoking status, n (%)
 Former smoker1.95 (1.66, 2.29)
 Current smoker1.16 (0.99, 1.36)0.068
Drinking status, n (%)
 Former drinker1.85 (1.58, 2.18)
 Current drinker0.50 (0.41, 0.62)
tHcy (μmol/L)1.01 (1.01, 1.02)
Serum uric acid (mmol/L)1.00 (1.00, 1.00)0.329
eGFR (ml/min)0.99 (0.99, 0.99)
Total bilirubin (mmol/L)0.99 (0.98, 1.00)0.255
Direct bilirubin (mmol/L)1.00 (0.98, 1.03)0.900
AST (U/L)1.00 (1.00, 1.00)0.372
ALT (U/L)1.00 (1.00, 1.01)0.183
Abdominal obesity, n (%)
 Yes0.83 (0.72, 0.96)
Hyperglycemia, n (%)
 Yes1.02 (0.89, 1.17)0.774
Elevated TG, n (%)
 Yes1.30 (1.14, 1.48)
Reduced HDL-C, n (%)
 Yes2.07 (1.80, 2.39)
BMI – body mass index; tHcy – total homocysteine; TC – total cholesterol; HDL-C – high-density lipoprotein cholesterol; eGFR – estimated glomerular filtration rate; AST – aspartate aminotransferase; ALT – alanine aminotransferase; T2DM – type 2 diabetes mellitus; Ref reference; OR – odds ratio; CI – confidence interval. Values are regression coefficients [OR (95% CI)] from univariate regression models and reflect differences in stroke occur per unit change of each covariate and for different categories of each covariate as compared to the reference group.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750