11 January 2022>: Clinical Research
Association Between Hyperhomocysteinemia Combined with Metabolic Syndrome and Higher Prevalence of Stroke in Chinese Adults Who Have Elevated Blood Pressure
Feng Hu 12BCDEF , Shichao Yu 3BCD , Juan Li 4ABCD , Wei Zhou 25BDEF , Tao Wang 25BCDE , Xiao Huang 125AF , Huihui Bao 125AG* , Xiaoshu Cheng 125AG*DOI: 10.12659/MSM.934100
Med Sci Monit 2022; 28:e934100
Supplementary Table 3 Effect size of HHcy and MS on cerebral stroke in different models.
Variables | Event, n (%) | Crude Model | Model I | Model II | |||
---|---|---|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | ||
Control | 175 (4.48%) | Ref | Ref | Ref | |||
Isolated HHcy | 315 (7.47%) | 1.72 (1.43, 2.08) | 1.44 (1.19, 1.76) | 1.32 (1.07, 1.62) | 0.008 | ||
Isolated MS | 192 (6.14%) | 1.40 (1.13, 1.72) | 0.002 | 1.54 (1.25, 1.91) | 1.78 (1.41, 2.23) | ||
HHcy+MS | 278 (9.90%) | 2.34 (1.93, 2.85) | 2.26 (1.86, 2.75) | 2.46 (1.97, 3.08) | |||
P for trend | |||||||
HHcy – hyperhomocysteinemia; MS – metabolic syndrome; Ref – reference; OR – odds ratio; CI – confidence interval. Model I adjusted for age and sex. Model II adjusted for sex, BMI, smoking and drinking status, eGFR, and serum uric acid. |