30 August 2021: Review Articles
A Review of the Increasing Prevalence of Metabolic-Associated Fatty Liver Disease (MAFLD) in Children and Adolescents Worldwide and in Mexico and the Implications for Public Health
Mariana M. Ramírez-Mejía 12ABCDEF , Luis E. Díaz-Orozco 23ABCDEF , Beatriz Barranco-Fragoso 4AEF , Nahum Méndez-Sánchez 23ACD*DOI: 10.12659/MSM.934134
Med Sci Monit 2021; 27:e934134
Background
Epidemiology of MAFLD in Adults Worldwide and in Mexico
Epidemiology of MAFLD in Children and Adolescents Worldwide and in Mexico
Risk Factors for MAFLD: Obesity, Type 2 Diabetes Mellitus, Metabolic Syndrome, and Genetics
Pathophysiology of MAFLD in Children and Adolescents
Diagnosis of MAFLD in Children and Adolescents
Prevention of MAFLD in Children and Adolescents
Conclusions
References
Table 1 Diagnostic criteria for Type 2 Diabetes Mellitus in children.
| Symptoms and/or hyperglycaemia |
| Symptoms of diabetes (polydipsia, polyuria, unexpleined weight loss) + Random plasma glucose >200 mg/dl |
| Fasting plasma glucose ≥126 mg/dl |
| Oral glucose tolerance test (75 gr glucose challenge) |
| Altered HbA1c |
| Adapted from American Diabetes Association’s diagnostic criteria recommendations []. HbA1c – hemoglobin A1c or glycated hemoglobin. |