A Review of the Increasing Prevalence of Metabolic-Associated Fatty Liver Disease (MAFLD) in Children and Adolescents Worldwide and in Mexico and the Implications for Public Health

30 August 2021 : Review article

Mariana M. Ramírez-Mejía^12ABCDEF, Luis E. Díaz-Orozco^23ABCDEF, Beatriz Barranco-Fragoso^4AEF, Nahum Méndez-Sánchez

^23ACD*

DOI: 10.12659/MSM.934134

Med Sci Monit 2021; 27:e934134

Background Epidemiology of MAFLD in Adults Worldwide and in Mexico Epidemiology of MAFLD in Children and Adolescents Worldwide and in Mexico Risk Factors for MAFLD: Obesity, Type 2 Diabetes Mellitus, Metabolic Syndrome, and Genetics Pathophysiology of MAFLD in Children and Adolescents Diagnosis of MAFLD in Children and Adolescents Prevention of MAFLD in Children and Adolescents Conclusions References

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Table 3 MAFLD diagnostic pearls.

Apply MAFLD criteria

Search for comorbidities

Consider metabolic syndrome

Do not use blood biomarkers or ICD alone

Perform transient elastography

Confirm the diagnosis with liver biopsy

ICD – International Classification of Diseases coding; MAFLD – Metabolic Associated Fatty Liver Disease.

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