30 August 2021: Review Articles
A Review of the Increasing Prevalence of Metabolic-Associated Fatty Liver Disease (MAFLD) in Children and Adolescents Worldwide and in Mexico and the Implications for Public Health
Mariana M. Ramírez-Mejía 12ABCDEF , Luis E. Díaz-Orozco 23ABCDEF , Beatriz Barranco-Fragoso 4AEF , Nahum Méndez-Sánchez 23ACD*DOI: 10.12659/MSM.934134
Med Sci Monit 2021; 27:e934134
Background
Epidemiology of MAFLD in Adults Worldwide and in Mexico
Epidemiology of MAFLD in Children and Adolescents Worldwide and in Mexico
Risk Factors for MAFLD: Obesity, Type 2 Diabetes Mellitus, Metabolic Syndrome, and Genetics
Pathophysiology of MAFLD in Children and Adolescents
Diagnosis of MAFLD in Children and Adolescents
Prevention of MAFLD in Children and Adolescents
Conclusions
References
Table 3 MAFLD diagnostic pearls.
| Apply MAFLD criteria |
| Search for comorbidities |
| Consider metabolic syndrome |
| Do not use blood biomarkers or ICD alone |
| Perform transient elastography |
| Confirm the diagnosis with liver biopsy |
| ICD – International Classification of Diseases coding; MAFLD – Metabolic Associated Fatty Liver Disease. |